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Colon Cancer clinical trials in Chicago, IL

13 studies for Colon Cancer are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Illinois Cancer Specialists, Chicago
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

PRE-ISPY Phase I/II Oncology Platform Program

RecruitingPhase 1/2
  • The University of Chicago Medicine Comprehensive Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05868226

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

RecruitingPhase 2/3
  • Mount Sinai Hospital Medical Center, Chicago
  • Northwestern University, Chicago
  • John H Stroger Jr Hospital of Cook County, Chicago
  • and 5 more
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05174169

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

Recruiting
  • John H Stroger Jr Hospital of Cook County, Chicago
Ages 45 to 70 · All sexes · Updated Sep 2, 2026 · NCT05080673

BMS-986504 in Combination With Pemetrexed for the Treatment of Metastatic Solid Tumors With MTAP Deletion

RecruitingPhase 1/2
  • Northwestern University, Chicago
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07594626

Shield Post-Approval Study Protocol

RecruitingObservational studyHealthy volunteers welcome
  • GI Solutions of Illinois, Chicago
  • GI Solutions of Illinois, Chicago
Ages 45 to 81 · All sexes · Updated Aug 7, 2026 · NCT06880055

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

RecruitingPhase 1
  • Xencor Investigative Site, Chicago
  • Xencor Investigative Site, Chicago
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05433142

Neoadjuvant Botensilimab and Balstilimab for the Treatment of Advanced Resectable Colorectal Cancer NEST3

RecruitingPhase 2
  • City of Hope at Illinois Chicago Downtown, Chicago
Ages 18 and older · All sexes · Updated Jul 1, 2026 · NCT07595874

A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

RecruitingPhase 1/2
  • University of Chicago, Chicago
Ages 12 and older · All sexes · Updated May 27, 2026 · NCT03093116

Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer

RecruitingObservational studyHealthy volunteers welcome
  • Section of Gastroenterology, Hepatology, and Nutrition, Department of Medicine University of Chicago Medicine, Chicago
Ages 18 to 49 · All sexes · Updated Apr 24, 2026 · NCT05732623

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer

RecruitingPhase 3
  • GSK Investigational Site, Chicago
  • GSK Investigational Site, Chicago
Ages 18 and older · All sexes · Updated Jan 23, 2026 · NCT05855200

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Chicago
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Colon Cancer trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.