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Colon Cancer clinical trials in Houston, TX

20 studies for Colon Cancer are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

RecruitingPhase 1
  • ALX Center 5, Houston
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07085091

A Study of PHN-012 in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • PHN-012-001 Site, Houston
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07127874

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Oncology Consultants P.A., Houston
  • Oncology Consultants P.A., Houston
  • Texas Oncology - Gulf Coast, Houston
  • and 7 more
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • MD Anderson, Houston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

RecruitingPhase 1/2
  • The University of Texas MD Anderson Cancer Center - Texas Medical Center, Houston
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

A Study of SHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07705334

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

RecruitingPhase 2/3
  • Lyndon Baines Johnson General Hospital, Houston
  • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston
  • Ben Taub General Hospital, Houston
  • and 2 more
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05174169

Shield Post-Approval Study Protocol

RecruitingObservational studyHealthy volunteers welcome
  • Integrity Advanced Therapeutics, PLLC, Houston
Ages 45 to 81 · All sexes · Updated Aug 7, 2026 · NCT06880055

A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • The University of Texas - M.D. Anderson Cancer Center, Houston
  • The University of Texas, MD Anderson Cancer Center - West Houston, Houston
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT07318805

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

RecruitingPhase 1
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07458347

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

RecruitingPhase 1
  • Research Site, Houston
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06835569

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • University of Texas, MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
Ages 12 and older · All sexes · Updated May 27, 2026 · NCT03093116

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas

RecruitingObservational study
  • M.D. Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated May 11, 2026 · NCT00843375

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06239194

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Houston
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Phase II Open-label Trial of Neoadjuvant Immunochemotherapy for Resectable Non-metastatic Colon cancER: NICER

RecruitingPhase 2
  • Baylor College of Medicine, Houston
Ages 18 to 80 · All sexes · Updated May 25, 2025 · NCT05870800

Colon Cancer trials in other cities

Other studies in Houston

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.