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Colon Cancer clinical trials in Boston, MA

22 studies for Colon Cancer are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Distance-Based Exercise to Preserve Function and Prevent Disability

Recruiting
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07059884

A Study of PHN-012 in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • PHN-012-001 Site, Boston
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07127874

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Brigham and Women's Hospital (BWH), Boston
  • Dana-Farber Cancer Institute (DFCI), Boston
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

RecruitingPhase 1/2
  • Massachusetts General Hospital - Main Campus, Boston
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

RecruitingPhase 3
  • Massachusetts General Hospital, Boston
  • Oncura Health, Boston
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07284849

Exercise for Gut Microbiome in Patients With Young-Onset Colorectal Cancer Undergoing Chemotherapy: The COURAGE Trial

Recruiting
  • Dana Farber Cancer Institute, Boston
Ages 18 to 50 · All sexes · Updated Sep 11, 2026 · NCT06202183

Resilience and Equity in Aging, Cancer, and Health (REACH)

Recruiting
  • Dana-Farber Cancer Institute, Boston
Ages 65 and older · All sexes · Updated Sep 10, 2026 · NCT04674267

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

Recruiting
  • Massachusetts General Hospital Cancer Center, Boston
Ages 45 to 70 · All sexes · Updated Sep 2, 2026 · NCT05080673

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

RecruitingPhase 2/3
  • Tufts Medical Center, Boston
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05174169

Clonal Hematopoiesis Chemotherapy and Radiation Effects Study

RecruitingObservational study
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Jun 30, 2026 · NCT07675967

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

RecruitingPhase 1
  • Mass General Brigham Cancer Institute at Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07458347

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

RecruitingPhase 1
  • Research Site, Boston
  • Research Site, Boston
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06835569

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • Massachusetts General Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

RecruitingPhase 1/2
  • Massachusetts General Hospital,, Boston
Ages 12 and older · All sexes · Updated May 27, 2026 · NCT03093116

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

Vitamin D in Patients With Stage I-III Colon Cancer or Resectable Colon Cancer Liver Metastases

RecruitingEarly phase 1
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated May 13, 2026 · NCT02172651

Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas

RecruitingObservational study
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated May 11, 2026 · NCT00843375

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06239194

Adaptive Randomization of Aerobic Exercise During Chemotherapy in Colon Cancer

Recruiting
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Jan 7, 2026 · NCT05773144

Building Connections

Recruiting
  • Disparities Research Unit, Massachusetts General Hospital, Boston
Ages 18 to 75 · All sexes · Updated Nov 18, 2025 · NCT07091032

Eliminating Barriers to Colorectal Cancer Screening Using Rapid Cycle Testing: A Pilot Study

RecruitingHealthy volunteers welcome
  • Codman Square Health Center, Boston
  • East Boston Neighborhood Health Center, East Boston · 2 mi away
Ages 18 and older · All sexes · Updated Nov 14, 2025 · NCT05524428

Colon Cancer trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.