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Glioblastoma clinical trials in Pittsburgh, PA

9 studies for Glioblastoma are looking for participants at sites in and around Pittsburgh (within about 30 miles). Open a study to see who can join and how to contact the study team.

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

RecruitingPhase 2
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07326566

Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment

RecruitingPhase 1/2
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05432804

Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care

RecruitingPhase 3
  • Allegheny Health Network, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07195591

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

RecruitingPhase 1
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06860594

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

RecruitingPhase 3
  • UPMC Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT05303519

INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)

RecruitingPhase 2
  • University of Pittsburgh Medical Center, Pittsburgh
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT02977780

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

RecruitingPhase 2/3
  • University of Pittsburgh Medical Center - Hillman Cancer Center, Pittsburgh
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT03970447

DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)

RecruitingPhase 2
  • UPMC Presbyterian Hospital, Pittsburgh
Ages 18 and older · All sexes · Updated Jul 1, 2026 · NCT06805305

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

RecruitingPhase 1
  • University of Pittsburg Medical Center (UPCM), Pittsburgh
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT05283330

Glioblastoma trials in other cities

Other studies in Pittsburgh

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.