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Major Depressive Disorder clinical trials in Portland, OR

5 studies for Major Depressive Disorder are looking for participants at sites in and around Portland (within about 30 miles). Open a study to see who can join and how to contact the study team.

Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression

RecruitingPhase 3
  • VA Portland Health Care System, Portland, OR, Portland
Ages 18 to 75 · All sexes · Updated Aug 14, 2026 · NCT07226232

A Study of Brenipatide in Adult Participants With Major Depressive Disorder

RecruitingPhase 3
  • Summit Headlands, Portland
Ages 18 to 75 · All sexes · Updated Aug 6, 2026 · NCT07412756

Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol

RecruitingPhase 3
  • Clinical Research Site, Portland
Ages 18 to 65 · All sexes · Updated Jul 24, 2026 · NCT07484217

Cognitive Rehabilitation for Veterans With MDD-related Cognitive Functioning Deficits

Recruiting
  • Portland VA Medical Center, Portland
Ages 18 and older · All sexes · Updated Jun 6, 2025 · NCT06728774

A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms

RecruitingPhase 4
  • Clinical Research Site, Portland
Ages 18 to 65 · All sexes · Updated Jan 23, 2025 · NCT06223880

Major Depressive Disorder trials in other cities

Other studies in Portland

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.