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Major Depressive Disorder clinical trials in Plano, TX

5 studies for Major Depressive Disorder are looking for participants at sites in and around Plano (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 2
  • Delricht Research - Plano, Plano
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07621237

Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder

RecruitingPhase 3
  • Vanda Investigational Site, Plano
Ages 18 to 65 · All sexes · Updated Sep 24, 2026 · NCT06830044

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

RecruitingPhase 3
  • Delricht Research - Plano, Plano
  • Aim Trials, Llc, Plano
Ages 18 to 74 · All sexes · Updated Aug 3, 2026 · NCT06775379

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

RecruitingPhase 2
  • Aim Trials, LLC, Plano
Ages 18 to 65 · All sexes · Updated May 11, 2026 · NCT06524830

Study of ALTO-300 in MDD

RecruitingPhase 2
  • Site 353, Plano
Ages 18 to 70 · All sexes · Updated Jul 24, 2025 · NCT05922878

Major Depressive Disorder trials in other cities

Other studies in Plano

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.