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Melanoma clinical trials in San Antonio, TX

15 studies for Melanoma are looking for participants at sites in and around San Antonio (within about 30 miles). Open a study to see who can join and how to contact the study team.

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

RecruitingPhase 1/2
  • START South Texas Accelerated Research Therapeutics, San Antonio
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05267626

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

RecruitingObservational study
  • The University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Audie L Murphy VA Hospital, San Antonio
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors

RecruitingPhase 1/2
  • South Texas Accelerated Research Therapeutics (START), LLC, San Antonio
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07070232

Project: Every Child for Younger Patients With Cancer

RecruitingObservational study
  • Children's Hospital of San Antonio, San Antonio
  • Methodist Children's Hospital of South Texas, San Antonio
  • University of Texas Health Science Center at San Antonio, San Antonio
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site, San Antonio
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07115043

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • UT Health Mays Cancer Center, San Antonio
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626

A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer Agents in Participants With Solid Tumors

RecruitingPhase 1
  • START San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT06880549

A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Clinical Trial Site, San Antonio
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT07749586

IDOV-Immune for Advanced Solid Tumors

RecruitingPhase 1
  • South Texas Accelerated Research Therapeutics, San Antonio
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06910657

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • Next Oncology, San Antonio
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body

RecruitingPhase 1/2
  • Next Oncology, San Antonio
  • The Start Center for Cancer Care, San Antonio
Ages 18 and older · All sexes · Updated Apr 28, 2026 · NCT06413680

A Phase 1/2 Clinical Trial to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMBD-501 in Patients With HER3-Expressing Solid Tumors

RecruitingPhase 1/2
  • Research Site, San Antonio
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT06956690

A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents

RecruitingPhase 1/2
  • NEXT Oncology, San Antonio
Ages 18 and older · All sexes · Updated Jan 7, 2025 · NCT06090266

Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

Recruiting
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Nov 27, 2024 · NCT03860883

About Melanoma

Melanoma is the most serious type of skin cancer. Most have a black or black-blue area. Learn the 'ABCDE' of what to watch for and treatment options.

More about Melanoma on MedlinePlus

Melanoma trials in other cities

Other studies in San Antonio

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.