Home › Breast Cancer › Ohio › Columbus
Breast Cancer clinical trials in Columbus, OH
39 studies for Breast Cancer are looking for participants at sites in and around Columbus (within about 30 miles). Open a study to see who can join and how to contact the study team.
Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
RecruitingObservational studyHealthy volunteers welcome
- Ohio State University Comprehensive Cancer Center, Columbus
- Mount Carmel East Hospital, Columbus
- The Mark H Zangmeister Center, Columbus
- and 8 more
A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer
RecruitingPhase 2
- The Ohio State University, Stefanie Spielman Comprehensive Breast Center, Columbus
BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors
RecruitingPhase 1
- James Cancer Hospital and Solove Research Institute, Columbus
A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
RecruitingPhase 1/2
- Local Institution - 0102, Columbus
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
RecruitingPhase 3
- Clinical Trial Site, Columbus
- Clinical Trial Site, Columbus
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
RecruitingPhase 3
- The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer -T, Columbus
A Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in Premenopausal Women With Early-stage and Advanced HR+ Breast Cancer
RecruitingPhase 1
- The Mark H. Zangmeister Center-Mid Ohio Oncology/Hematology, Inc., Columbus
A Study of Sofe-M in Participants With Selected Advanced Solid Tumors
RecruitingPhase 1
- The Ohio State University (OSU) Wexner Medical Center, Columbus
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
RecruitingPhase 3
- Ohio State University Comprehensive Cancer Center, Columbus
- Columbus Oncology and Hematology Associates Inc, Columbus
- Riverside Methodist Hospital, Columbus
- and 8 more
ATEMPT 2.0: Adjuvant T-DM1 vs TH
RecruitingPhase 2
- Stefanie Spielman Comprehensive Breast Center, Columbus
Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial
RecruitingPhase 3
- Ohio State University Comprehensive Cancer Center, Columbus
Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction
RecruitingPhase 2Healthy volunteers welcome
- Ohio State University Comprehensive Cancer Center, Columbus
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
RecruitingPhase 1/2
- Ohio State University Comprehensive Cancer Center (OSUCCC)- The James Cancer Hospital and Solove Research Institute, Columbus
E-Mindfulness Approaches for Living After Breast Cancer
RecruitingPhase 3
- Ohio State University Comprehensive Cancer Center, Columbus
- Mount Carmel East Hospital, Columbus
- Mount Carmel Grove City Hospital, Grove City · 7 mi away
- and 2 more
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
RecruitingPhase 2
- The Ohio State University Comprehensive Cancer Center (OSUCCC) - The James Cancer Hospital and Solove Research Institute, Columbus
First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
RecruitingPhase 1/2
- Stefanie Spielman Comprehensive Breast Center, Columbus
Abemaciclib Dose Escalation to Maintain Intensity (ADE-MI)
RecruitingPhase 4
- Ohio State University Comprehensive Cancer Center, Columbus
Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer
RecruitingPhase 2
- Ohio State University Comprehensive Cancer Center, Columbus
A Pilot Study to Evaluate the Effectiveness of Focused Massage on Pain, Mobility, and Quality of Life During Radiation Treatment for Patients With Breast Cancer
Recruiting
- The Ohio State University, Columbus
Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
RecruitingPhase 3
- The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solovev Research Institute (OSUCCC - , Columbus
Impact of Dietary Inflammatory Potential on Breast Cancer Risk
RecruitingObservational study
- Ohio State University Comprehensive Cancer Center, Columbus
Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation
RecruitingPhase 1
- Ohio State University-James Cancer Hospital and Solove Research Institute, Columbus
Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Breast Cancer w/Liver Dominant Disease
RecruitingPhase 2
- Ohio State University, Stefanie Spielman Comprehensive Breast Center, Columbus
Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)
RecruitingPhase 3
- Stefanie Spielman Comprehensive Breast Center at Olentangy River Road, Columbus
I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
RecruitingPhase 2
- The Ohio State University, Stefanie Spielman Comprehensive Breast Center, Columbus
Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC
RecruitingPhase 2
- Ohio State University Medical Center, Columbus
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
RecruitingPhase 3
- Ohio State University Comprehensive Cancer Center, Columbus
- Mount Carmel East Hospital, Columbus
- Riverside Methodist Hospital, Columbus
- and 8 more
Myeloid-Derived Suppressor Cell Function in Breast Cancer Patients
RecruitingObservational study
- Ohio State University Comprehensive Cancer Center, Columbus
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
RecruitingPhase 1/2
- Stefanie Spielman Comprehensive Breast Center, Columbus
Living Well With Advanced Breast Cancer
RecruitingObservational studyHealthy volunteers welcome
- Ohio State University Comprehensive Cancer Center, Columbus
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
RecruitingObservational study
- Memorial Hospital, Marysville · 27 mi away
Feasibility Study of CBCT for IGRT in Cancer Patients
Recruiting
- James Outpatient Center, Columbus
- Ohio State University, Brain and Spine Hospital, Columbus
- The Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus
- and 1 more
The Sleep After Breast Cancer (ABC) Study - Examining Sleep Changes and Biomarkers Among Breast Cancer Patients
RecruitingObservational study
- Ohio State University Comprehensive Cancer Center, Columbus
The Ohio State University (OSU) SCREEN Community Program
RecruitingHealthy volunteers welcome
- Ohio State University Comprehensive Cancer Center, Columbus
A Study of MT-4561 in Patients With Various Advanced Solid Tumors
RecruitingPhase 1/2
- The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer Center, Columbus
DAANCE FOR CHEMOTHERAPY-INDUCED NEUROPATHY
RecruitingPhase 2
- The Ohio State University, Columbus
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
RecruitingObservational study
- Massive Bio SYNERGY-AI site, Columbus
Pilot Study of a MIND Diet Intervention in Women Undergoing Active Treatment for Breast Cancer
Recruiting
- Ohio State University Comprehensive Cancer Center, Columbus
IORT Following Breast Conserving Surgery for Early Stage Breast Cancer Registry
RecruitingObservational study
- Mount Carmel West Hospital, Columbus
About Breast Cancer
Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.
More about Breast Cancer on MedlinePlus
Breast Cancer trials in other cities
- New York City, NY134 studies
- Houston, TX126 studies
- Boston, MA111 studies
- Nashville, TN80 studies
- Los Angeles, CA72 studies
- Edison, NJ68 studies
- St. Louis, MO64 studies
- Durham, NC63 studies
- Queens, NY63 studies
- Chicago, IL58 studies
- Philadelphia, PA56 studies
- Dallas, TX55 studies
Other studies in Columbus
- Non-Small Cell Lung Cancer56 studies
- Ovarian Cancer39 studies
- Cancer (all types)38 studies
- Lung Cancer37 studies
- Acute Myeloid Leukemia35 studies
- Chronic Lymphocytic Leukemia28 studies
- Metastatic Cancer27 studies
- Endometrial Cancer25 studies
- Colorectal Cancer24 studies
- Prostate Cancer24 studies
- Multiple Myeloma24 studies
- Melanoma21 studies
From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.