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Cancer (all types) clinical trials in Cleveland, OH
36 studies for Cancer (all types) are looking for participants at sites in and around Cleveland (within about 30 miles). Open a study to see who can join and how to contact the study team.
Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →
A Study to Assess Change in Disease Activity and Adverse Events in Adult Participants With Gynecologic Cancers Receiving Intravenous Infusion of IMGN151 as Monotherapy or in Combination With Other Therapies
RecruitingPhase 2
- University Hospitals Cleveland Medical Center /ID# 279601, Cleveland
A Study of ASP3082 in Adults With Advanced Solid Tumors
RecruitingPhase 1
- Case Western, Cleveland
A First-in-Human Study of KK2223 in Participants With Relapsed or Refractory T Cell Non-Hodgkin Lymphoma
RecruitingPhase 1
- University Hospitals Cleveland Medical Center, Cleveland
Visugromab in Cachexia International Trial
RecruitingPhase 2/3
- Cleveland Clinic (Main Campus), Cleveland
- Cleveland Clinic Hillcrest Hospital, Mayfield Heights · 12 mi away
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
RecruitingPhase 2/3
- University Hospitals of Cleveland, Cleveland
- Cleveland Clinic Foundation, Cleveland
Statins to Prevent Cancer Associated Blood Clots
RecruitingPhase 4
- Cleveland Clinic Foundation, Cleveland
Replacing Invasive Cystoscopy With Urine Testing for Non-muscle Invasive Bladder Cancer Surveillance
RecruitingPhase 2
- University Hospitals Cleveland Medical Center, Cleveland
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
RecruitingPhase 2
- Cleveland Clinic, Cleveland
A Phase 1/1b Study of IAM1363 in HER2 Cancers
RecruitingPhase 1
- University Hospital Cleveland Medical Center, Cleveland
- Cleveland Clinic, Cleveland
A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)
RecruitingObservational study
- Cleveland Clinic, Cleveland
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
RecruitingPhase 3
- Cleveland Clinic, Cleveland
Project: Every Child for Younger Patients With Cancer
RecruitingObservational study
- Rainbow Babies and Childrens Hospital, Cleveland
- Cleveland Clinic Foundation, Cleveland
A Study of REC-1245 in Participants With Unresectable, Locally Advanced, or Metastatic Cancer
RecruitingPhase 1/2
- Cleveland Clinic, Cleveland
Abatacept in Immune Checkpoint Inhibitor Myocarditis
RecruitingPhase 3
- Cleveland Clinic, Cleveland
FOG-001 in Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
- University Hospitals Cleveland Medical Center, Seidman Cancer Center, Cleveland
- Cleveland Clinic, Cleveland
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
RecruitingPhase 3
- Case Western Reserve University, Cleveland
- Cleveland Clinic Cancer Center/Fairview Hospital, Cleveland
- Cleveland Clinic Foundation, Cleveland
- and 3 more
Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast
RecruitingPhase 2
- University Hospitals Cleveland Medical Center, Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland
- Cleveland Clinic Taussig Cancer Center, Case Comprehensive Cancer Center, Cleveland
Feasibility and Acceptability of Wearable Sensors and ePROs in Early Phase Clinical Trials
Recruiting
- Case Comprehensive Cancer Center, Cleveland Clinic Foundation Taussig Cancer Institute, Cleveland
A Study of ASP1002 in Adults for Treatment of Solid Tumors
RecruitingPhase 1
- University Hospitals of Cleveland, Cleveland
First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
RecruitingPhase 1/2
- UH Cleveland Medical Center, Cleveland
A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment Pumitamig (BNT327) and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer
RecruitingPhase 1/2
- Cleveland Clinic Taussig Cancer Institute Case Comprehensive Cancer Center, Cleveland
Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC
RecruitingPhase 1/2
- University Hospitals Cleveland Medical Center, Cleveland
Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI
Recruiting
- Louis Stokes VA Medical Center, Cleveland, OH, Cleveland
A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors
RecruitingPhase 1
- University Hospitals - UH Cleveland Medical Center, Cleveland
I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
RecruitingPhase 2
- Cleveland Clinic, Cleveland
CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)
RecruitingPhase 1/2
- Cleveland Clinic, Cleveland
Proton Therapy Patient Registry
RecruitingObservational study
- University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center, Cleveland
Suprachoroidal Administration in Subjects With Metastases to the Choroid
RecruitingPhase 2
- Cleveland Clinic, Cole Eye Institute, Cleveland
Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy
Recruiting
- Louis Stokes VA Medical Center, Cleveland, OH, Cleveland
Caris Biorepository Research Protocol
RecruitingObservational studyHealthy volunteers welcome
- Great Lakes Medical Research, Cleveland
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
RecruitingObservational study
- Massive Bio SYNERGY-AI site, Mayfield Heights · 12 mi away
A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs
RecruitingPhase 1/2
- Cleveland Clinic, Cleveland
Promoting Access, Resources and Treatment Through Novel and Equitable Solutions for Cancer Care
Recruiting
- Case Comprehensive Cancer Center, Cleveland
Phase 1 Study Evaluating BA3182 in Patients With Advanced Adenocarcinoma.
RecruitingPhase 1
- University Hospitals Cleveland Medical Center, Cleveland
A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
- Cleveland Clinic, Cleveland
Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
Recruiting
- University Hospitals Cleveland Medical Centre, Cleveland
- University Hospitals Chagrin Highlands Medical Centre, Orange · 12 mi away
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Cancer (all types) trials in other cities
- Houston, TX121 studies
- New York City, NY110 studies
- Boston, MA86 studies
- Los Angeles, CA73 studies
- Nashville, TN65 studies
- Philadelphia, PA59 studies
- Durham, NC58 studies
- Washington, DC58 studies
- Chicago, IL51 studies
- Seattle, WA49 studies
- Atlanta, GA49 studies
- Arlington, VA48 studies
Other studies in Cleveland
- Non-Small Cell Lung Cancer43 studies
- Breast Cancer35 studies
- Prostate Cancer34 studies
- Heart Failure33 studies
- Metastatic Cancer30 studies
- Ovarian Cancer30 studies
- Lung Cancer26 studies
- Colorectal Cancer24 studies
- Cardiovascular Disease22 studies
- Endometrial Cancer20 studies
- Acute Myeloid Leukemia20 studies
- Crohn's Disease19 studies
From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.