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Colorectal Cancer clinical trials in Denver, CO

23 studies for Colorectal Cancer are looking for participants at sites in and around Denver (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Kaiser Permanente-Franklin, Denver
Ages 45 to 75 · All sexes · Updated Oct 5, 2026 · NCT06995898

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • Rocky Mountain Cancer Center, Denver
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • AdventHealth Porter, Denver
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Intermountain Health Cancer Center Saint Joseph, Denver
  • Intermountain Health Saint Joseph Hospital - Research Office, Denver
  • Intermountain Health Saint Joseph Hospital, Denver
  • and 3 more
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9

RecruitingPhase 1/2
  • SCRI at HCA Health One, Denver
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT07186842

A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer

RecruitingPhase 1
  • SCRI Denver, Denver
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT07227168

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute at HealthOne, Denver
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06586515

A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute, Denver
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT07066657

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Rocky Mountain Cancer Center, Denver
  • Sarah Cannon Research Institute at HealthONE, Denver
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04657068

A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

RecruitingPhase 1
  • Sarah Cannon Research Institue At Healthone, Denver
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT06179160

A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

RecruitingPhase 3
  • Rocky Mountain Cancer Centers, LLP, Denver
  • Rocky Mountain Cancer Centers, LLP, Denver
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT05253651

A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types

RecruitingPhase 1
  • Sarah Cannon Research Institute at HealthONE, Denver
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT07503808

CT-95 in Advanced Cancers Associated With Mesothelin Expression

RecruitingPhase 1
  • Context Investigational Site, Denver
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06756035

A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)

RecruitingPhase 2
  • Rocky Mountain Cancer Center - Primary, Denver
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07011576

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute at HealthONE, Denver
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT06026410

Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

RecruitingPhase 1/2
  • SCRI - Denver, Denver
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT03947385

Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer

RecruitingObservational studyHealthy volunteers welcome
  • Department of Medicine-Gastroenterology, Denver Veterans Affairs Medical Center, University of Colorado Hospital, Denver
Ages 18 to 49 · All sexes · Updated Apr 24, 2026 · NCT05732623

A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

RecruitingPhase 1
  • Sarah Cannon Cancer Institute at HealthONE, Denver
Ages 18 and older · All sexes · Updated Apr 23, 2026 · NCT06720987

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Kaiser Permanente-Franklin, Denver
  • Colorado Blood Cancer Institute, Denver
  • Rocky Mountain Cancer Centers-Midtown, Denver
  • and 1 more
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Sarah Cannon Research Institute at HealthONE, Denver
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07030257

About Colorectal Cancer

Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.

More about Colorectal Cancer on MedlinePlus

Colorectal Cancer trials in other cities

Other studies in Denver

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.