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Melanoma clinical trials in San Diego, CA

18 studies for Melanoma are looking for participants at sites in and around San Diego (within about 30 miles). Open a study to see who can join and how to contact the study team.

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DESTINY-PANTUMOUR04

RecruitingObservational study
  • Research Site, San Diego
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Pan-tumor MRD Study

RecruitingObservational study
  • Medical Oncology Associates of San Diego (MOASD), San Diego
  • Medical Oncology Associates of San Diego, San Diego
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06605404

Comparing the Effectiveness of Less Invasive Procedures With the Current Standard of Care for the Treatment of Older Adults With Early-Stage Melanoma

RecruitingPhase 3
  • UC San Diego Moores Cancer Center, La Jolla · 11 mi away
Ages 75 and older · All sexes · Updated Sep 24, 2026 · NCT07068074

Intratumoral N17350 in Advanced Solid Tumors

RecruitingPhase 1/2
  • Scripps Clinic Torrey Pines - La Jolla, San Diego
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07339176

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

RecruitingPhase 2
  • Sharp Memorial Hospital, San Diego
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04511013

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

RecruitingObservational study
  • University of California, San Diego, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors

RecruitingPhase 1/2
  • University of California-San Diego, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07287917

A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

RecruitingPhase 1
  • University of California San Diego, Moores Cancer Center, San Diego
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT04913285

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

RecruitingPhase 1/2
  • UC San Diego Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT05896839

Project: Every Child for Younger Patients With Cancer

RecruitingObservational study
  • Rady Children's Hospital - San Diego, San Diego
  • Naval Medical Center -San Diego, San Diego
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

Binimetinib and Imatinib for Unresectable Stage III-IV KIT-Mutant Melanoma

RecruitingPhase 2
  • UC San Diego Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT04598009

Neoadjuvant Darovasertib in Primary Uveal Melanoma

RecruitingPhase 3
  • UCSD Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07015190

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

RecruitingPhase 2/3
  • UC San Diego Moores Cancer Center, La Jolla · 11 mi away
All ages · All sexes · Updated Apr 2, 2026 · NCT06581406

A Phase 1/2 Clinical Trial to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMBD-501 in Patients With HER3-Expressing Solid Tumors

RecruitingPhase 1/2
  • Research Site, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT06956690

A Study to Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3

RecruitingObservational study
  • UC San Diego Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Jan 12, 2026 · NCT06887348

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, La Jolla · 11 mi away
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Beta-only IL-2 ImmunoTherapY Study

RecruitingPhase 1/2
  • Sharp Memorial Hospital, San Diego
Ages 18 and older · All sexes · Updated Jul 9, 2025 · NCT05086692

Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies

RecruitingPhase 1
  • UC San Diego Moores Cancer Center, La Jolla · 11 mi away
Ages 18 and older · All sexes · Updated Feb 8, 2024 · NCT04282044

About Melanoma

Melanoma is the most serious type of skin cancer. Most have a black or black-blue area. Learn the 'ABCDE' of what to watch for and treatment options.

More about Melanoma on MedlinePlus

Melanoma trials in other cities

Other studies in San Diego

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.