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Prostate Cancer clinical trials in Saint Paul, MN

13 studies for Prostate Cancer are looking for participants at sites in and around Saint Paul (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
  • Minnesota Oncology Hematology PA-Maplewood, Maplewood · 5 mi away
  • and 3 more
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • Health Partners Cancer Center at Regions Hospital, Saint Paul
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

RecruitingPhase 2
  • Regions Hospital, Saint Paul
  • Lakeview Hospital, Stillwater · 16 mi away
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

RecruitingPhase 3
  • HealthPartners Cancer Research Center-HealthPartners Cancer Center at Regions Hospital ( Site 0092), Saint Paul
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06136650

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

RecruitingPhase 3
  • HealthPartners Cancer Center at Regions Hospital ( Site 0052), Saint Paul
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT06925737

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

RecruitingPhase 3
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
  • Lakeview Hospital, Stillwater · 16 mi away
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

RecruitingPhase 3
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
  • Minnesota Oncology Hematology PA-Maplewood, Maplewood · 5 mi away
  • and 3 more
Ages 18 and older · Men · Updated Aug 19, 2026 · NCT04423211

Water Vapor Ablation for Prostate Cancer: Long-Term Registry

RecruitingObservational study
  • Minnesota Urology, Woodbury · 7 mi away
All ages · Men · Updated Aug 18, 2026 · NCT07455058

Axelopran for Advanced Cancer in Patients Receiving Opioids

RecruitingPhase 2
  • HealthPartners Cancer Center at Regions Hospital, Saint Paul
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT07354919

Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body

RecruitingPhase 3
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
  • Minnesota Oncology Hematology PA-Maplewood, Maplewood · 5 mi away
  • and 3 more
Ages 18 and older · Men · Updated Jan 22, 2026 · NCT06470243

Vitamin D for Prostate Endocrine Therapy

RecruitingPhase 3
  • Regions Hospital, Saint Paul
  • Minnesota Oncology Hematology PA-Maplewood, Maplewood · 5 mi away
  • Saint John's Hospital - Healtheast, Maplewood · 5 mi away
Ages 50 and older · Men · Updated Jan 15, 2026 · NCT05838716

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site 121, Saint Paul
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

RecruitingPhase 3
  • Regions Hospital, Saint Paul
Ages 18 and older · Men · Updated Sep 11, 2025 · NCT03678025

About Prostate Cancer

Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.

More about Prostate Cancer on MedlinePlus

Prostate Cancer trials in other cities

Other studies in Saint Paul

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.