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Cardiovascular Disease clinical trials in Philadelphia, PA

21 studies for Cardiovascular Disease are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

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ELEVATE-HFpEF Clinical Study

Recruiting
  • Lankenau Institute for Medical Research, Wynnewood · 7 mi away
Ages 40 and older · All sexes · Updated Oct 2, 2026 · NCT06678841

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

RecruitingPhase 2
  • Suburban Research Associates, West Chester · 24 mi away
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07783802

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

RecruitingPhase 3
  • Thomas Jefferson University, Philadelphia
  • Tristar Clinical Investigations PC, Philadelphia
  • Suburban Research Associates, West Chester · 24 mi away
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07064473

Product Surveillance Registry

RecruitingObservational study
  • Philadelphia, Philadelphia
All ages · All sexes · Updated Sep 18, 2026 · NCT01524276

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

RecruitingPhase 3
  • Clinical Trial Site, Philadelphia
  • Clinical Trial Site, Media · 12 mi away
  • Clinical Trial Site, Horsham · 16 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07181109

Zenith® Fenestrated+ Clinical Study

Recruiting
  • Hospital of the University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT04875429

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Recruiting
  • Lankenau Medical Center, Wynnewood · 7 mi away
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

Recruiting
  • Thomas Jefferson University Hospital, Philadelphia
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

RecruitingPhase 3
  • Perelman School of Medicine, Philadelphia
Ages 18 to 100 · All sexes · Updated Sep 4, 2026 · NCT07517263

Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

Recruiting
  • Hospital of the University of Pennsylvania, Philadelphia
Ages 18 to 85 · All sexes · Updated Sep 3, 2026 · NCT06703489

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • Thomas Jefferson University, Philadelphia
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma

RecruitingObservational study
  • Children's Hospital of Philadelphia, Philadelphia
  • Alfred I duPont Hospital for Children, Wilmington · 25 mi away
Ages 7 and older · All sexes · Updated Aug 25, 2026 · NCT05705531

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

RecruitingPhase 3
  • Research Site, Philadelphia
  • Research Site, Philadelphia
  • Research Site, Horsham · 16 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

RecruitingPhase 3
  • University of Pennsylvania, Philadelphia
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Recruiting
  • University of Pennsylvania, Philadelphia
  • Abington Memorial Hospital, Abington · 12 mi away
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

LCAT (Lecithin Cholesterol Acyl Transferase) Natural History Study

RecruitingObservational study
  • University of Pennsylvania, Philadelphia
All ages · All sexes · Updated May 6, 2026 · NCT06217588

Pivotal Study for the Cardiac Performance System (CPS)

RecruitingObservational study
  • University of Pennsylvania - Penn Presbyterian Medical Center, Philadelphia
Ages 18 and older · All sexes · Updated Apr 24, 2026 · NCT06870591

Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiography Trial

RecruitingPhase 3
  • Montefiore Medical Center - Bronx, Philadelphia
Ages 35 to 80 · All sexes · Updated Apr 16, 2026 · NCT07293260

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Recruiting
  • University of Pennsylvania, Philadelphia
  • Lankenau Institute of Medical Research, Wynnewood · 7 mi away
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Philly CEAL- DECIDE+ Adaptation

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 35 to 75 · All sexes · Updated Oct 1, 2025 · NCT06732102

PARTNER 3 Trial - Aortic Valve-in-Valve

Recruiting
  • University of Pennsylvania Hospital, Philadelphia
  • Lankenau Medical Center, Wynnewood · 7 mi away
All ages · All sexes · Updated May 10, 2024 · NCT03003299

Cardiovascular Disease trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.