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Colorectal Cancer clinical trials in New York City, NY
78 studies for Colorectal Cancer are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.
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AVA6103 in Subjects With Locally Advanced or Metastatic Selected Solid Tumors
RecruitingPhase 1
- Memorial Sloan Kettering Cancer Center, New York
Developing New Educational Materials About Genetic Testing for a Diverse Group of Cancer Patients
Recruiting
- Memorial Sloan Kettering at Ralph Lauren Center (Limited Protocol Activities), New York
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer
RecruitingPhase 2
- Perlmutter Cancer Center at NYU Langone Health (contact for more locations), New York
A Study of Mental Health Care in People With Cancer
Recruiting
- Memorial Sloan Kettering Cancer Center, New York
Colonoscopy vs Stool Testing for Older Adults With Colon Polyps
Recruiting
- New York Harbor Health Care System - Dept of Veterans Affairs, New York
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
RecruitingPhase 1/2
- Columbia University Medical Center, New York
- Memorial Sloan Kettering, New York
Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial
RecruitingPhase 2
- Mount Sinai West, New York
- Mount Sinai Hospital, New York
- Manhattan Eye Ear and Throat Hospital, New York
- and 3 more
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
RecruitingObservational studyHealthy volunteers welcome
- NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
RecruitingPhase 1
- Exelixis Clinical Site #60, New York
- Exelixis Clinical Site #6, New York
Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
RecruitingPhase 1
- Columbia University Irving Medical Center, New York
- Memorial Sloan Kettering Cancer Center, New York
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
RecruitingPhase 1/2
- Memorial Sloan-Kettering Cancer Center, New York
A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
RecruitingPhase 1
- Research Site, New York
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
RecruitingPhase 3
- North Shore Hematology Oncology Associates P.C. DBA New York Cancer and Blood Specialists, New York
A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)
RecruitingPhase 1/2
- Laura and Isaac Perlmutter Cancer Center at NYU Langone ( Site 0324), New York
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
RecruitingPhase 3
- NYU Langone Medical Center NYU Hematology Associates, New York
Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
RecruitingObservational study
- NYU Langone Medical Center, New York
A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer
RecruitingPhase 1/2
- NYU Langone Long Island Clinical Research Associates, New York
- Herbert Irving Comprehensive Cancer Center Columbia University Medical Center, New York
Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors
RecruitingPhase 1
- Research Site, New York
- Research Site, New York
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
RecruitingPhase 3
- Mount Sinai, New York
- Mount Sinai West, New York
- NYU Langone Medical Center NYU Hematology Associates, New York
- and 1 more
Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial
RecruitingPhase 3
- Mount Sinai Hospital, New York
- Memorial Sloan Kettering Cancer Center, New York
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
RecruitingPhase 1
- New York University (NYU) Langone Medical Center, New York
- David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center, New York
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
RecruitingPhase 1
- New York University (NYU) Clinical Cancer Center, New York
- David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center, New York
A Study of Botensilimab and Balstilimab for Colorectal Cancer With ctDNA+ After Surgery and Chemotherapy
RecruitingPhase 2
- Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
RecruitingPhase 1/2
- Columbia University Medical Center, New York
- Memorial Sloan Kettering Cancer Center Main Campus, New York
Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
RecruitingPhase 1/2
- Columbia University, New York
- NYU Langone Health, New York
- Memorial Sloan Kettering Cancer Center, New York
A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations
RecruitingPhase 1/2
- NYU Langone Health Perlmutter Cancer Center, New York
Tislelizumab in People With Colorectal Cancer
RecruitingPhase 2
- Memorial Sloan Kettering Cancer Center, New York
Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors
RecruitingPhase 1
- Laura and Isaac Perlmutter Cancer Center at NYU Langone Health, New York
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
RecruitingPhase 1/2
- NYU Langone Medical Center - Perlmutter Cancer Center (NYU Cancer Institute), New York
- Memorial Sloan Kettering Cancer Center, New York
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
RecruitingPhase 3
- Icahn School of Medicine At Mount Sinai, New York
- Memorial Sloan Kettering Cancer Center, New York
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)
RecruitingPhase 1
- New York Cancer and Blood Specialists-Central Park Hematology & Oncology, New York
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
RecruitingPhase 3
- Clinical Study Site, New York
A Study of Sofe-M in Participants With Selected Advanced Solid Tumors
RecruitingPhase 1
- New York University (NYU) Clinical Cancer Center, New York
- David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center, New York
A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients With Refractory Advanced/Metastatic Colorectal Cancer
RecruitingPhase 2
- NYU Langone Health, New York
A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors
RecruitingPhase 1
- Memorial Sloan Kettering Cancer Center, New York
A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9
RecruitingPhase 1/2
- Memorial Sloan Kettering Cancer Center, New York
A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer
RecruitingPhase 1
- Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
RecruitingPhase 1/2
- NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
RecruitingPhase 1
- New York University (NYU) Langone Medical Center, New York
- David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center, New York
FOG-001 in Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
- Memorial Sloan Kettering Cancer Center, New York
Neoadjuvant Dupilumab and Toripalimab in MSS CRC Subjects With Resectable Liver Metastases
RecruitingPhase 1/2
- Icahn School of Medicine at Mount Sinai, New York
A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
RecruitingPhase 1/2
- NYU Langone Health, New York
- Icahn School of Medicine At Mount Sinai Prime, New York
A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed (EMBOLD PanGI-201)
RecruitingPhase 1/2
- GSK Investigational Site, New York
- GSK Investigational Site, New York
Discovering New Targets for Colorectal and Endometrial Cancer Risk Reduction
RecruitingObservational studyHealthy volunteers welcome
- NYP/Weill Cornell Medicine, New York
A Study of Meaning-Centered Therapy for Mexican Adults With Advanced Cancer
Recruiting
- Memorial Sloan Kettering Cancer Center, New York
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
RecruitingPhase 1/2
- Mt. Sinai, New York
- Memorial Sloan Kettering Cancer Center, New York
A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
RecruitingPhase 1
- Weill Cornell Medicine, New York
- Memorial Sloan Kettering Cancer Center, New York
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
RecruitingPhase 3
- Rockefeller Outpatient Pavilion (53rd Street), New York
- Memorial Solan Kettering Cancer Center- Main Campus, New York
A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors
RecruitingPhase 1
- Memorial Sloan Kettering Cancer Center - David H. Koch Center for Cancer Care (74th Street)., New York
- Memorial Sloan Kettering Cancer Center 53rd street., New York
- Memorial Sloan Kettering Cancer Center - Main Campus, New York
A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors
RecruitingPhase 1
- David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center, New York
- Icahn School of Medicine at Mount Sinai, New York
Safely Optimizing Body Weight With Mifomelatide (TCMCB07) in Patients With Newly Diagnosed Colorectal Cancer (CRC) or Pancreatic Ductal Adenocarcinoma (PDAC) Undergoing Chemotherapy
RecruitingPhase 2
- NYU Langone Health Perlmutter Cancer Center, New York
A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors
RecruitingPhase 2
- Memorial Sloan Kettering Cancer Center, New York
Anastomotic Safety and Surveillance Using Real-time Enhanced Sensing Using xBar
Recruiting
- Weill Cornell Medicine Colon and Rectal Surgery, New York
- Department of Colon and Rectal Surgery, New York
A Study of a Urine Test to Detect Colorectal Cancer
RecruitingObservational study
- Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
RecruitingPhase 1/2
- NYU Langone Medical Center, New York
A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations
RecruitingPhase 1
- Research Site, New York
- Research Site, New York
Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors
RecruitingPhase 1
- NYU Langone, New York
- Memorial Sloan Kettering Cancer Center, New York
Evaluating the Implementation of a Comprehensive Multilevel Virtual Oncology Program Among Veterans Diagnosed With Lung, Colorectal, Prostate, and Breast Cancers in the US Department of Veterans Affairs
Recruiting
- VA New York Harbor Health Care System - Manhattan, New York
- VA New York Harbor Healthcare System - Harlem Community Center, New York
BBO-11818 in Adult Subjects With KRAS Mutant Cancer
RecruitingPhase 1
- NYU Langone Health, New York
- Columbia University Irving Medical Center, New York
A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors
RecruitingPhase 1
- Memorial Sloan Kettering Cancer Center, New York
Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases
RecruitingPhase 2
- Weill Cornell Medicine/NewYork-Presbyterian Hospital, New York
Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
RecruitingPhase 1/2
- Perlmutter Cancer Center at NYU Langone Health, New York
- Memorial Sloan-Kettering Cancer Center, New York
- Columbia University, New York
A Study of MGC028 in Participants With Advanced Solid Tumors
RecruitingPhase 1
- Icahn School of Medicine at Mt. Sinai, New York
A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
RecruitingPhase 1/2
- Laura & Isaac Perlmutter Cancer Center at NYU Langone, New York
FITting Non-invasive Tests in Lynch Syndrome Surveillance
RecruitingObservational study
- Columbia University, New York
Changes in Reproductive and Sexual Health in People With Early Onset Colorectal Cancer
RecruitingObservational study
- Memorial Sloan Kettering Cancer Center, New York
An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.
RecruitingPhase 2
- NGM Clinical Study Site, New York
Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors
RecruitingPhase 3Healthy volunteers welcome
- NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
RecruitingPhase 1/2
- Laura & Isaac Perlmutter Cancer Center at NYU Langone Health, New York
- Memorial Sloan Kettering Cancer Center, New York
Biopsy After Radioembolization to Identify Changes in Tumor Cells From the Radiation
RecruitingObservational study
- Memorial Sloan Kettering Cancer Center, New York
Combination Immunotherapy for the Treatment of Chemotherapy-refractory Metastatic MSS CRC
RecruitingPhase 1/2
- Icahn School of Medicine at Mount Sinai, New York
A Study of Single Fraction Stereotactic Body Radiation Therapy (SBRT) Guided by Magnetic Resonance Imaging (MRI) in People With Liver Metastasis From Colorectal Cancer
RecruitingPhase 2
- Memorial Sloan Kettering Cancer Center (All protocol activities), New York
Collection of Information to Better Understand Young Onset Colorectal Cancer
RecruitingObservational study
- MSK at Ralph Lauren, New York
- Memorial Sloan Kettering Cancer Center, New York
LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia
RecruitingObservational study
- Manhattan Eye Ear and Throat Hospital, New York
- Lenox Hill Hospital, New York
Community Health Workers United to Reduce Colorectal Cancer and Cardiovascular Disease Among People at Higher Risk
RecruitingHealthy volunteers welcome
- Columbia University Irving Medical Center, New York
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
RecruitingPhase 1/2
- NYU Langone Health, New York
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
RecruitingPhase 1
- Memorial Sloan Kettering, New York
- Columbia University Herbert Irving Comprehensive Cancer Center, New York
A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)
RecruitingPhase 1/2
- Memorial Sloan-Kettering Cancer Center, New York
About Colorectal Cancer
Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.
More about Colorectal Cancer on MedlinePlus
Colorectal Cancer trials in other cities
- Houston, TX102 studies
- Nashville, TN69 studies
- Boston, MA63 studies
- Los Angeles, CA59 studies
- Arlington, VA52 studies
- St. Louis, MO50 studies
- San Antonio, TX46 studies
- Philadelphia, PA44 studies
- Grand Rapids, MI40 studies
- Baldwin Park, CA37 studies
- Chicago, IL34 studies
- Tampa, FL34 studies
Other studies in New York City
- Breast Cancer136 studies
- Non-Small Cell Lung Cancer121 studies
- Cancer (all types)109 studies
- Prostate Cancer103 studies
- Metastatic Cancer93 studies
- Ovarian Cancer69 studies
- Lung Cancer60 studies
- Multiple Myeloma60 studies
- Pancreatic Cancer60 studies
- Endometrial Cancer52 studies
- Acute Myeloid Leukemia51 studies
- Heart Failure51 studies
From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.