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Mild Cognitive Impairment clinical trials in Philadelphia, PA

11 studies for Mild Cognitive Impairment are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)

RecruitingPhase 2
  • Pennsylvania Hospital, Philadelphia
Ages 55 to 85 · All sexes · Updated Sep 22, 2026 · NCT07589595

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

RecruitingPhase 3
  • Flourish Research ? Philadelphia, Plymouth Meeting · 12 mi away
Ages 50 to 90 · All sexes · Updated Sep 21, 2026 · NCT07177352

Percepta for Cognitive Optimization

Recruiting
  • Reputable Health, Wilmington · 25 mi away
Ages 40 to 85 · All sexes · Updated Sep 17, 2026 · NCT07612449

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

RecruitingPhase 3
  • Keystone Clinical Studies, Plymouth Meeting · 12 mi away
Ages 60 to 85 · All sexes · Updated Sep 17, 2026 · NCT06976203

Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY

RecruitingObservational study
  • The Hospital of the University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT04916210

Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders

Recruiting
  • Hospital of the University of Pennsylvania, Philadelphia
Ages 70 and older · All sexes · Updated Sep 8, 2026 · NCT05929703

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • Thomas Jefferson University, Philadelphia
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

Neurobehavioral Changes Following Spaceflight Stressors

RecruitingHealthy volunteers welcome
  • University of Pennsylvania Perelman School of Medicine, Philadelphia
Ages 21 to 60 · All sexes · Updated Aug 6, 2026 · NCT07293494

Sense4Safety Intervention

RecruitingPhase 1/2
  • University of Pennsylvania, Philadelphia
Ages 65 and older · All sexes · Updated Mar 19, 2026 · NCT07220668

Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke

Recruiting
  • Penn Medicine Rehabilitation, Philadelphia
Ages 18 to 90 · All sexes · Updated Jan 9, 2026 · NCT04897334

Surviving Daily Life

RecruitingObservational study
  • Thomas Jefferson University, Philadelphia
Ages 40 and older · Women · Updated Oct 22, 2025 · NCT07054723

About Mild Cognitive Impairment

In mild cognitive impairment (MCI), you have more memory and thinking problems than others your age, but they don't interfere with your everyday life.

More about Mild Cognitive Impairment on MedlinePlus

Mild Cognitive Impairment trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.