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Multiple Sclerosis clinical trials in Knoxville, TN

4 studies for Multiple Sclerosis are looking for participants at sites in and around Knoxville (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity

RecruitingPhase 2
  • Hope Neurology, Knoxville
Ages 18 to 70 · All sexes · Updated Oct 1, 2026 · NCT06782490

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

RecruitingObservational study
  • TG Therapeutics Investigational Trial Site, Knoxville
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06433752

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

RecruitingPhase 2
  • Alliance for Multispecialty Research Clinical, Knoxville
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07002034

Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis

RecruitingPhase 3
  • Hope Neurology- Site Number : 8400019, Knoxville
Ages 18 to 60 · All sexes · Updated Sep 15, 2026 · NCT07325292

About Multiple Sclerosis

Multiple sclerosis (MS) slows down or blocks messages between the brain and body. MS can be mild or severe. Learn about MS symptoms and treatment.

More about Multiple Sclerosis on MedlinePlus

Multiple Sclerosis trials in other cities

Other studies in Knoxville

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.