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Multiple Sclerosis clinical trials in Cleveland, OH

9 studies for Multiple Sclerosis are looking for participants at sites in and around Cleveland (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

RecruitingObservational study
  • TG Therapeutics Investigational Trial Site, Cleveland
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06433752

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

RecruitingPhase 2
  • Cleveland Clinic, Cleveland
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07002034

A Study to Assess the Safety and Clinical Activity of Azer-cel in Participants With B-cell Mediated Autoimmune Disorders

RecruitingPhase 1
  • TG Therapeutics Investigational Trial Site, Cleveland
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06680037

An Open-label Study of AZD0120 in Adults With Multiple Sclerosis

RecruitingPhase 1
  • Research Site, Cleveland
Ages 18 to 60 · All sexes · Updated Aug 25, 2026 · NCT07224373

Electrical Stimulation Exercise for Individuals With Lower Limb Paralysis

Recruiting
  • Louis Stokes Cleveland VA Medical Center, Cleveland
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07768761

Understanding and Enhancing Human Health and Movement

Recruiting
  • Louis Stokes Cleveland VA Medical Center, Cleveland
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07738978

Care in Multiple Sclerosis (MS)

RecruitingObservational study
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT07011914

Central Vein Sign in Multiple Sclerosis Extension Study

Recruiting
  • Cleveland Clinic Foundation, Cleveland
Ages 18 to 65 · All sexes · Updated Feb 20, 2026 · NCT07424027

Impact of the Cionic Neural Sleeve on Mobility in Multiple Sclerosis

Recruiting
  • Cleveland State University, Cleveland
Ages 22 to 75 · All sexes · Updated Sep 24, 2025 · NCT05964829

About Multiple Sclerosis

Multiple sclerosis (MS) slows down or blocks messages between the brain and body. MS can be mild or severe. Learn about MS symptoms and treatment.

More about Multiple Sclerosis on MedlinePlus

Multiple Sclerosis trials in other cities

Other studies in Cleveland

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.