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Sickle Cell Disease clinical trials in Charlotte, NC

7 studies for Sickle Cell Disease are looking for participants at sites in and around Charlotte (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

RecruitingPhase 3
  • Atrium Levine Children's/Atrium Health, Charlotte
Ages 2 and older · All sexes · Updated Sep 18, 2026 · NCT06609226

A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

RecruitingPhase 1/2Healthy volunteers welcome
  • Levine Cancer Insitute Carolinas Healthcare System, Charlotte
Ages 12 to 55 · All sexes · Updated Sep 9, 2026 · NCT06546670

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

RecruitingObservational study
  • St. Jude Affiliate Clinic at Novant Health Hemby Children's Hospital, Charlotte
All ages · All sexes · Updated Aug 17, 2026 · NCT04398628

Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

RecruitingObservational study
  • Atrium Health (MRD-HCT), Charlotte
Ages 3 to 20 · All sexes · Updated Jun 4, 2026 · NCT06941389

Sickle Cell Clinical Research and Intervention Program

RecruitingObservational study
  • Novant Health Hemby Children's Hospital, Charlotte
All ages · All sexes · Updated Jun 4, 2026 · NCT02098863

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

RecruitingPhase 3
  • Levine Children's Hospital - Hematology, Charlotte
Ages 12 to 35 · All sexes · Updated Mar 23, 2026 · NCT05477563

Minimizing Toxicity in HLA-identical Sibling Donor Transplantation for Children With Sickle Cell Disease

RecruitingPhase 2
  • Levine Children's Hospital, Charlotte
Ages 2 to 25 · All sexes · Updated Mar 10, 2026 · NCT03587272

About Sickle Cell Disease

Sickle cell disease is a group of inherited disorders that affect your red blood cells. It can cause pain, anemia, and other problems. Learn about treatments.

More about Sickle Cell Disease on MedlinePlus

Sickle Cell Disease trials in other cities

Other studies in Charlotte

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.