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Bladder Cancer clinical trials recruiting in the U.S.
142 studies for Bladder Cancer are recruiting participants at sites across the United States.
Bladder cancer symptoms range from lower back pain to blood in your urine. Read about important risk factors and find a list of treatments available
Cities with the most studies
- New York City, NY35 studies
- Nashville, TN31 studies
- Houston, TX31 studies
- Dallas, TX27 studies
- Boston, MA26 studies
- Washington, DC26 studies
- Los Angeles, CA24 studies
- Baltimore, MD24 studies
- St. Louis, MO22 studies
- Philadelphia, PA21 studies
- Seattle, WA21 studies
- Edison, NJ21 studies
- Chicago, IL21 studies
- Durham, NC20 studies
- Columbus, OH19 studies
- Cleveland, OH18 studies
- Queens, NY16 studies
- Atlanta, GA16 studies
- Baldwin Park, CA14 studies
- San Francisco, CA13 studies
- Portland, OR13 studies
- San Antonio, TX13 studies
- Rochester, MN12 studies
- Kansas City, KS12 studies
- Austin, TX12 studies
- Orange, CA12 studies
- Grand Rapids, MI12 studies
- San Diego, CA11 studies
- Birmingham, AL11 studies
- Milwaukee, WI11 studies
- Denver, CO11 studies
- Irvine, CA11 studies
- Detroit, MI11 studies
- New Rochelle, NY11 studies
- Staten Island, NY11 studies
- Minneapolis, MN11 studies
- Oklahoma City, OK11 studies
- Kansas City, MO10 studies
- Myrtle Beach, SC10 studies
- Omaha, NE10 studies
By state
- Alabama11 studies
- Alaska3 studies
- Arizona20 studies
- Arkansas15 studies
- California54 studies
- Colorado20 studies
- Connecticut9 studies
- Delaware4 studies
- District of Columbia17 studies
- Florida38 studies
- Georgia19 studies
- Idaho6 studies
- Illinois30 studies
- Indiana14 studies
- Iowa12 studies
- Kansas17 studies
- Kentucky7 studies
- Louisiana13 studies
- Maryland36 studies
- Massachusetts31 studies
- Michigan25 studies
- Minnesota24 studies
- Mississippi3 studies
- Missouri27 studies
- Montana7 studies
- Nebraska11 studies
- Nevada5 studies
- New Hampshire3 studies
- New Jersey26 studies
- New Mexico3 studies
- New York41 studies
- North Carolina26 studies
- North Dakota4 studies
- Ohio36 studies
- Oklahoma12 studies
- Oregon14 studies
- Pennsylvania27 studies
- Rhode Island4 studies
- South Carolina16 studies
- South Dakota4 studies
- Tennessee34 studies
- Texas51 studies
- Utah14 studies
- Vermont3 studies
- Virginia24 studies
- Washington25 studies
- West Virginia5 studies
- Wisconsin17 studies
- Wyoming4 studies
Recently updated studies
Evaluation for NCI Surgery Branch Clinical Research Protocols
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT00001823A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069KEYMAKER-U04 Substudy 04D: A Clinical Study of New Treatments Given With Enfortumab Vedotin and Pembrolizumab in People With Urothelial Cancer (MK-3475-04D/KEYMAKER-U04)
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07232602En-bloc Transurethral Resection of Bladder Tumor (En-bloc TURBT) Specimens Using a Redesigned Surgical Resectoscope Device
RecruitingObservational study
Ages 18 to 120 · All sexes · Updated Oct 2, 2026 · NCT04235764Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07000084Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06770582A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06760819Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06764095A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06833073A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07090499Futibatinib in Combination With Durvalumab Prior to Cystectomy for the Treatment of Muscle-Invasive Bladder Cancer Patients Who Are Ineligible for Cisplatin-based Therapy
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06263153Imaging Study of [89Zr]DFO-YS5 for Cancer Detection
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07664397Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07061964Enfortumab Vedotin and Pembrolizumab Combined With Radiotherapy in Muscle Invasive Bladder Cancer
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06470282Enfortumab Vedotin and Stereotactic Radiation for Localized Bladder Cancer
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06394570Enfortumab Vedotin, Pembrolizumab and Quemliclustat for the Treatment of Unresectable Locally Advanced and Metastatic Urothelial Cancer
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07667335Collection of Serum and Tissue Samples From Patients With Biopsy-Proved or Suspected Malignant Disease
RecruitingObservational studyHealthy volunteers welcome
Ages 2 and older · All sexes · Updated Sep 30, 2026 · NCT00026884Patient-Centered Surgical Prehabilitation
RecruitingHealthy volunteers welcome
Ages 18 to 85 · All sexes · Updated Sep 30, 2026 · NCT05715684The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07285044Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07566156Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382DK222 Study at Hopkins
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07140315Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07421700From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.