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Healthy volunteer studies in San Antonio, TX

77 studies at sites in and around San Antonio accept healthy volunteers — people without the condition being studied. Many studies pay participants for their time and travel; the amount is set by each study, so ask the study team.

Fertilo In Vitro Research Study and Trial

RecruitingPhase 3Healthy volunteers welcome
  • Aspire Fertility San Antonio, San Antonio
Ages 18 to 35 · Women · Updated Sep 29, 2026 · NCT06858111

Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis

RecruitingPhase 1/2Healthy volunteers welcome
  • Xencor Investigative Site, San Antonio
Ages 18 to 75 · All sexes · Updated Sep 29, 2026 · NCT06619990

Ph 1a/1b Single Ascending Dose and Multiple Ascending Dose Study of ARQ-234

RecruitingPhase 1Healthy volunteers welcome
  • Clinical Site 104, San Antonio
Ages 18 to 65 · All sexes · Updated Sep 29, 2026 · NCT07453602

First-in-Human Trial to Assess REGN20423 in Healthy Adult Participants and Adult Participants With Atopic Dermatitis

RecruitingPhase 1Healthy volunteers welcome
  • Texas Dermatology and Laser Specialists, San Antonio
Ages 18 to 65 · All sexes · Updated Sep 25, 2026 · NCT07527923

Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older

RecruitingPhase 1/2Healthy volunteers welcome
  • DM Clinical Research - San Antonio - North San Saba- Site Number : 8400056, San Antonio
  • DM Clinical Research - San Antonio - North San Saba- Site Number : 8400057, San Antonio
Ages 60 and older · All sexes · Updated Sep 24, 2026 · NCT07734649

Behavioral Economic Intervention to Improve HIV Behaviors in Sexual Minority Individuals

RecruitingHealthy volunteers welcome
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 to 34 · All sexes · Updated Sep 23, 2026 · NCT06745947

Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)

RecruitingHealthy volunteers welcome
  • The University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 to 65 · All sexes · Updated Sep 22, 2026 · NCT02969798

Pioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants

RecruitingPhase 4Healthy volunteers welcome
  • Texas Diabetes Institute/UH, San Antonio
Ages 30 to 70 · All sexes · Updated Sep 22, 2026 · NCT05838287

Effect of Hepatic Impairment on the Pharmacokinetics of Mirdametinib

RecruitingPhase 1Healthy volunteers welcome
  • American Research Corporation (Texas Liver Institute), San Antonio
Ages 18 to 80 · All sexes · Updated Sep 21, 2026 · NCT06997276

A Study to Evaluate the Effect of Moderate or Severe Hepatic Impairment on the Pharmacokinetics (PK) of Inavolisib

RecruitingPhase 1Healthy volunteers welcome
  • The Texas Liver Institute, Inc., San Antonio
  • Pinnacle Clinical Research - San Antonio, San Antonio
Ages 18 to 80 · All sexes · Updated Sep 18, 2026 · NCT07144111

A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age

RecruitingPhase 3Healthy volunteers welcome
  • GSK Investigational Site, San Antonio
Ages 65 and older · All sexes · Updated Sep 18, 2026 · NCT07805707

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

RecruitingPhase 3Healthy volunteers welcome
  • ACCOMPLISH-2 Research Site, San Antonio
  • ACCOMPLISH-2 Research Site, San Antonio
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

A First-in-Human Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of HMB-003 in Healthy Volunteers

RecruitingPhase 1Healthy volunteers welcome
  • Worldwide Clinical Trials, San Antonio
Ages 18 to 50 · All sexes · Updated Sep 10, 2026 · NCT07798505

A Phase I Study to Investigate the Pharmacokinetics and Safety of Capivasertib in Participants With Moderate Hepatic Impairment

RecruitingPhase 1Healthy volunteers welcome
  • Research Site, San Antonio
Ages 18 to 80 · All sexes · Updated Sep 9, 2026 · NCT07343960

A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.

RecruitingPhase 3Healthy volunteers welcome
  • Sun Research Institute, San Antonio
42 Days – 211 Days · All sexes · Updated Sep 8, 2026 · NCT07629440

A First-in-human Research Study on How NNC0721-8060 Works in People Living With Overweight or Obesity

RecruitingPhase 1Healthy volunteers welcome
  • ICON, San Antonio
Ages 18 to 55 · All sexes · Updated Sep 4, 2026 · NCT07767175

Comparative PK Assessment Study of Casdatifan in Moderate Hepatically Impaired Participants Versus Matched Participants With Normal Hepatic Function

RecruitingPhase 1Healthy volunteers welcome
  • Research Site, San Antonio
Ages 18 to 84 · All sexes · Updated Sep 4, 2026 · NCT07751250

A Study to Test How BI 1291583 is Taken up in the Blood of People With and Without Liver Problems

RecruitingPhase 1Healthy volunteers welcome
  • American Research Corporation at the Texas Liver Institute, San Antonio
Ages 18 to 80 · All sexes · Updated Sep 4, 2026 · NCT07023354

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

RecruitingHealthy volunteers welcome
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07091617

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Audie L Murphy VA Hospital, San Antonio
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

A Phase I Study to Investigate the Effect of Hepatic Impairment of AZD9550 and AZD6234

RecruitingPhase 1Healthy volunteers welcome
  • Research Site, San Antonio
Ages 18 to 85 · All sexes · Updated Sep 1, 2026 · NCT07546760

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • San Antonio VA Medical Center, San Antonio
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

A Study of LY4174794 in Participants With Obesity or Overweight Who Are Otherwise Healthy

RecruitingPhase 1Healthy volunteers welcome
  • ICON Early Phase Services, LLC, San Antonio
Ages 18 to 65 · All sexes · Updated Sep 1, 2026 · NCT07654972

Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents

RecruitingPhase 3Healthy volunteers welcome
  • Sun Research Institute, San Antonio
15 Months – 17 Years · All sexes · Updated Aug 31, 2026 · NCT07660198

A Study to Assess Zilucoplan Concentration in Breast Milk of Healthy Lactating Women

RecruitingPhase 1Healthy volunteers welcome
  • UP0137 2, San Antonio
Ages 18 and older · Women · Updated Aug 27, 2026 · NCT06961747

Genetic of Skeletal Muscle Insulin Resistance

RecruitingHealthy volunteers welcome
  • Texas Diabetes Institute - University Health System, San Antonio, Texas 78207, San Antonio
Ages 18 to 75 · All sexes · Updated Aug 24, 2026 · NCT07780513

Advancing Skills Through Consultation, Education, and Novel Technologies

RecruitingHealthy volunteers welcome
  • University of Texas Health Science Center at San Antonio, San Antonio
All ages · All sexes · Updated Aug 24, 2026 · NCT07707102

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight

RecruitingPhase 1Healthy volunteers welcome
  • ICON Early Phase Services, San Antonio
Ages 18 to 65 · All sexes · Updated Aug 20, 2026 · NCT07738614

First Time in Human Study of Long Acting VH4524184 Formulations

RecruitingPhase 1Healthy volunteers welcome
  • GSK Investigational Site, San Antonio
Ages 18 to 55 · All sexes · Updated Aug 10, 2026 · NCT06310551

A Study of LY4088044 in Healthy Participants

RecruitingPhase 1Healthy volunteers welcome
  • ICON Early Phase Services, San Antonio
Ages 18 to 65 · All sexes · Updated Aug 7, 2026 · NCT07090785

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

RecruitingObservational studyHealthy volunteers welcome
  • UT San Antonio Health Science Center, San Antonio
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04363684

Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth in/Near Infected Bone Cavities

RecruitingHealthy volunteers welcome
  • UT Health San Antonio, San Antonio
Ages 22 and older · All sexes · Updated Jul 14, 2026 · NCT05361941

Assessment of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of a New Formulation of Inclisiran Containing Polysorbate 80 Compared to the Currently Marketed Formulation

RecruitingPhase 1Healthy volunteers welcome
  • Cardiovasular Renal Metabolism, San Antonio
Ages 18 to 60 · All sexes · Updated Jul 10, 2026 · NCT07626281

Study of GS-4571 in Healthy Participants, Nondiabetic Obese Participants, and Nonobese Participants With Type 2 Diabetes Mellitus (T2DM)

RecruitingPhase 1Healthy volunteers welcome
  • ICON Early Phase Services, LLC, San Antonio
Ages 18 to 55 · All sexes · Updated Jun 22, 2026 · NCT06562907

Text-Based Messaging Strategies for Preventing Subsequent Problematic Alcohol Use

RecruitingHealthy volunteers welcome
  • JBSA Lackland, San Antonio
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT06318975

Pharmacokinetic Study of Vorasidenib in Severe Hepatically Impaired and Matched-Control Participants

RecruitingPhase 1Healthy volunteers welcome
  • American Research Corporation, San Antonio
Ages 18 to 75 · All sexes · Updated Jun 5, 2026 · NCT07250633

A Study of Eloralintide (LY3841136) in Participants With Different Levels of Liver Damage and in Participants With Healthy Livers.

RecruitingPhase 1Healthy volunteers welcome
  • American Research Corporation, San Antonio
Ages 18 to 85 · All sexes · Updated Jun 4, 2026 · NCT07401862

A Phase 1/2a Study of DB-2304 in Healthy Adults and SLE/CLE Participants

RecruitingPhase 1/2Healthy volunteers welcome
  • US02-0, San Antonio
Ages 18 to 70 · All sexes · Updated Jun 2, 2026 · NCT06625671

Modifying Adiposity Through Behavioral Strategies to Improve COVID-19 Rehabilitation

RecruitingHealthy volunteers welcome
  • South Texas Health Care System, San Antonio, TX, San Antonio
Up to age 80 · All sexes · Updated Jun 1, 2026 · NCT05880108

RESTOR: PK/PD mTORi Inhibition in Older Adults

RecruitingEarly phase 1Healthy volunteers welcome
  • The University of Texas Health Science Center at San Antonio, San Antonio
Ages 65 to 90 · All sexes · Updated Jun 1, 2026 · NCT06658093

Genomic Predictors of Recurrent Pregnancy Loss

RecruitingObservational studyHealthy volunteers welcome
  • University of Texas at San Antonio, San Antonio
Ages 18 to 50 · All sexes · Updated May 22, 2026 · NCT05444283

A Study to Test How BI 3000202 is Taken up in the Blood of People With and Without Liver Problems

RecruitingPhase 1Healthy volunteers welcome
  • American Research Corporation at the Texas Liver Institute, San Antonio
Ages 18 to 80 · All sexes · Updated May 14, 2026 · NCT07486102

A Study of Mirikizumab Solution (LY3074828) in Healthy Participants

RecruitingPhase 1Healthy volunteers welcome
  • Worldwide Clinical Trials, Inc., San Antonio
Ages 18 to 65 · All sexes · Updated May 14, 2026 · NCT07446101

The Role of Glucagon in Glucose Metabolism in Humans With and Without Bariatric Surgery

RecruitingPhase 1Healthy volunteers welcome
  • Texas Diabetes Institute - University Health System, San Antonio
  • University of Texas San Antonio, San Antonio
Ages 18 to 65 · All sexes · Updated May 11, 2026 · NCT07212868

Radiprodil in Participants With Hepatic Impairment

RecruitingPhase 1Healthy volunteers welcome
  • Texas Liver Institute, San Antonio
Ages 18 to 75 · All sexes · Updated May 8, 2026 · NCT07457229

Use of CA125 and Complementary Biomarkers for the Early Detection of Ovarian Cancer in Low Risk Women

RecruitingHealthy volunteers welcome
  • UT Health Science Center San Antonio, San Antonio
Ages 50 to 74 · Women · Updated May 6, 2026 · NCT00539162

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of EDP-978 in Healthy Adults

RecruitingPhase 1Healthy volunteers welcome
  • ICON Early Phase, San Antonio
Ages 18 to 65 · All sexes · Updated Apr 21, 2026 · NCT07540910

A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist Use

RecruitingPhase 3Healthy volunteers welcome
  • Vanda Investigational Site, San Antonio
Ages 18 to 65 · All sexes · Updated Apr 20, 2026 · NCT07446439

Quitxt Mobile Text Messaging Cessation Research Study

RecruitingHealthy volunteers welcome
  • The University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 to 29 · All sexes · Updated Mar 31, 2026 · NCT05958667

Neonatal Platelet Transfusion Threshold Trial

RecruitingHealthy volunteers welcome
  • Pediatrix Medical Group, San Antonio
1 Hour – 48 Hours · All sexes · Updated Mar 25, 2026 · NCT06676904

A Study to Evaluate the Effects of CYP2D6 Phenotypes on the Pharmacokinetics of Xanomeline Following KarXT Administration in Healthy Adult Participants

RecruitingPhase 1Healthy volunteers welcome
  • ICON Development Solutions, San Antonio
Ages 18 to 65 · All sexes · Updated Feb 19, 2026 · NCT07204418

Cognitive Screening Made Easy for PCPs - Administrative Supplement

RecruitingHealthy volunteers welcome
  • UT Health San Antonio's Geriatrics and Supportive Care Clinic, San Antonio
Ages 60 and older · All sexes · Updated Feb 5, 2026 · NCT06928298

Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study

RecruitingObservational studyHealthy volunteers welcome
  • University of Texas, San Antonio
Ages 18 and older · All sexes · Updated Jan 15, 2026 · NCT05677880

Wound Healing Following Tooth Extraction and Ridge Preservation Using OsteoGen®

RecruitingHealthy volunteers welcome
  • University of Texas Health Science Center at San Antonio School of Dentistry, San Antonio
Ages 18 to 89 · All sexes · Updated Jan 6, 2026 · NCT07154693

Chromosome 18 Clinical Research Center

RecruitingObservational studyHealthy volunteers welcome
  • University Health Systems Hospital, San Antonio
  • University of Texas Health Science Center at San Antonio, San Antonio
All ages · All sexes · Updated Jan 6, 2026 · NCT00227253

Passive Detection- SARS-CoV-2 (COVID-19) A&M Breathalyzer (PROTECT Kiosk) for Operational Medicine

RecruitingObservational studyHealthy volunteers welcome
  • Brooke Army Medical Center, Fort Sam Houston · 4 mi away
Ages 18 to 89 · All sexes · Updated Dec 10, 2025 · NCT06402318

A Study to Evaluate the SENSE Device's Ability to Detect TBI

RecruitingObservational studyHealthy volunteers welcome
  • UTSA, San Antonio
Ages 22 and older · All sexes · Updated Nov 25, 2025 · NCT06828107

Ultrasound for Healthy Aging

RecruitingHealthy volunteers welcome
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 70 and older · All sexes · Updated Nov 17, 2025 · NCT07168525

Microsurgery and Periodontal Healing

RecruitingHealthy volunteers welcome
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 to 18 · All sexes · Updated Nov 12, 2025 · NCT07054008

The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness

RecruitingHealthy volunteers welcome
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 to 18 · All sexes · Updated Nov 12, 2025 · NCT07053969

Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions

RecruitingObservational studyHealthy volunteers welcome
  • University of Texas Health Science Center, San Antonio
All ages · All sexes · Updated Oct 15, 2025 · NCT03160274

An Advanced Decision Support Tool for Personalized Medicine for IVF Using Modeling and Optimization for Provera

RecruitingPhase 1/2Healthy volunteers welcome
  • Positivf Fertility, San Antonio
Ages 20 to 50 · Women · Updated Sep 29, 2025 · NCT07148999

Role of Neural and Hormonal Regulation Factors on Insulin Secretion After Gastric Bypass Surgery

RecruitingEarly phase 1Healthy volunteers welcome
  • Texas Diabetes Institute - University Health System, San Antonio
  • South Texas Veterans Health Care System, San Antonio
Ages 18 to 65 · All sexes · Updated Sep 9, 2025 · NCT00992901

Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass

RecruitingEarly phase 1Healthy volunteers welcome
  • Texas Diabetes Institute - University Health System, San Antonio
  • South Texas Veterans Health Care System, San Antonio
Ages 18 to 65 · All sexes · Updated Sep 9, 2025 · NCT01803451

The Effects of Bariatric Surgeries on Glucose Metabolism

RecruitingEarly phase 1Healthy volunteers welcome
  • Texas Diabetes Institute - University Health System, San Antonio
  • South Texas Veterans Health Care System, San Antonio
Ages 18 to 65 · All sexes · Updated Sep 9, 2025 · NCT02823665

Combining Stellate Ganglion Block With Prolonged Exposure for PTSD

RecruitingPhase 2Healthy volunteers welcome
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 to 65 · All sexes · Updated Sep 4, 2025 · NCT05889741

Evaluation of a Device to Reduce Motion Sickness and Spatial Disorientation

RecruitingHealthy volunteers welcome
  • Randolph AFB Physiology lab, San Antonio
Ages 18 to 50 · All sexes · Updated Aug 15, 2025 · NCT06892340

CONTOURA vs WFO Ablation PRK & LASIK

RecruitingHealthy volunteers welcome
  • Joint Warfighter Refractive Surgery Center at WHASC, San Antonio
Ages 21 to 50 · All sexes · Updated Aug 14, 2025 · NCT05037370

Safety and Immunogenicity of a Self-Amplifying RNA Vaccine Against Crimean-Congo Hemorrhagic Fever

RecruitingPhase 1Healthy volunteers welcome
  • Flourish Research San Antonio (Clinical Trials of Texas), San Antonio
Ages 18 to 64 · All sexes · Updated Jul 28, 2025 · NCT06799013

Pharmacokinetics (PK) and Safety of Zanzalintinib in Participants With Moderate Hepatic Impairment (HI)

RecruitingPhase 1Healthy volunteers welcome
  • Exelixis Clinical Site #2, San Antonio
Ages 18 to 75 · All sexes · Updated Jun 22, 2025 · NCT06962332

InSpace Accelerated Rehabilitation Study

RecruitingHealthy volunteers welcome
  • TSAOG Orthopaedics & Spine, San Antonio
Ages 65 and older · All sexes · Updated May 29, 2025 · NCT05329584

Phosphatidylethanol and Other Ethanol Consumption Markers

RecruitingHealthy volunteers welcome
  • University of Texas Health Science Center San Antonio, San Antonio
Ages 21 and older · All sexes · Updated May 13, 2025 · NCT06747364

Collection of Sputum and Labeling for Lung Cancer

RecruitingObservational studyHealthy volunteers welcome
  • South Texas Veterans Health Care System (STVHCS)/Audie L. Murphy Memorial Veterans Hospital, San Antonio
Ages 21 and older · All sexes · Updated Apr 1, 2025 · NCT03457415

The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD

RecruitingPhase 4Healthy volunteers welcome
  • Brooke Army Medical Center, San Antonio
Ages 18 to 70 · All sexes · Updated Feb 25, 2025 · NCT06414356

Using SnapshotNIR With Provocative Leg Maneuver for PAD Assessment

RecruitingObservational studyHealthy volunteers welcome
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 35 to 99 · All sexes · Updated Oct 10, 2024 · NCT06237621

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.