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Breast Cancer clinical trials in Pittsburgh, PA
39 studies for Breast Cancer are looking for participants at sites in and around Pittsburgh (within about 30 miles). Open a study to see who can join and how to contact the study team.
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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
RecruitingPhase 1/2
- University of Pittsburgh Medical Center, Pittsburgh
Phase IIIb Study of Ribociclib + ET in Early Breast Cancer
RecruitingPhase 3
- Allegheny Health Network, Pittsburgh
Distance-Based Exercise to Preserve Function and Prevent Disability
Recruiting
- UPMC Hillman Cancer Center, Pittsburgh
A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer
RecruitingPhase 2
- University of Pittsburgh (UPMC), Pittsburgh
Prospective Study of EXErcise Regimens After Treatment for Breast Cancer for Hypertrophy and Conditioning
RecruitingObservational study
- Allegheny General Hospital, Pittsburgh
A Pilot Study Assessing Myokines During an EXErcise Regimen After Treatment for Breast Cancer
Recruiting
- AHN Allegheny General Hospital, Pittsburgh
- Allegheny General Hospital, Pittsburgh
A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
RecruitingPhase 1
- Research Site, Pittsburgh
EXERT-BC Protein: Protein Supplementation to Improve Body Composition After Treatment for Breast Cancer
Recruiting
- AHN Allegheny General Hospital, Pittsburgh
- AHN Allegheny General Hospital, Pittsburgh
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
RecruitingPhase 3
- University of Pittsburgh Medical Center Magee-Womens Hospital ( Site 0058), Pittsburgh
Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy
Recruiting
- University of Pittsburgh Cancer Institute (UPCI), Pittsburgh
Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
Recruiting
- Allegheny (AHN), Pittsburgh
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
RecruitingPhase 1
- University of Pittsburgh Medical Center, Pittsburgh
Identifying Patterns in the Breath of Individuals With Breast Cancer
RecruitingObservational studyHealthy volunteers welcome
- Weinstein Imaging Associates, Pittsburgh
Active Surveillance in Older Women With ER+ Breast Cancer
RecruitingObservational study
- University of Pittsburgh Medical Center, Pittsburgh
A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies
RecruitingPhase 1/2
- Research Site, Pittsburgh
A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer
RecruitingPhase 1/2
- UPMC - Hillman Cancer Center, Pittsburgh
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
RecruitingPhase 3
- UPMC Hillman Cancer Center - Magee-Women?s Hospital, Pittsburgh
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
RecruitingPhase 3
- Allegheny General Hospital, Pittsburgh
- UPMC-Magee Womens Hospital, Pittsburgh
- West Penn Hospital, Pittsburgh
- and 10 more
A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors
RecruitingPhase 1
- UPMC Hillman Cancer Center, Pittsburgh
A Phase 1 Study of LNCB74 in Advanced Solid Tumors
RecruitingPhase 1
- UPMC, Pittsburgh
ATEMPT 2.0: Adjuvant T-DM1 vs TH
RecruitingPhase 2
- University of Pittsburgh Medical Center Cancer UPMC- Magee Women's Hospital, Pittsburgh
Biennial CEM in Women With a Personal History of Breast Cancer
RecruitingHealthy volunteers welcome
- Magee-Womens Hospital, Pittsburgh
- Hillman Cancer Center at Shadyside, Pittsburgh
- UPMC Magee-Womens Imaging - Bethel Park, Bethel Park · 8 mi away
- and 3 more
EXERT-BC Cardio: Cardio or Conditioning Training With Breast Cancer
Recruiting
- AHN Allegheny General Hospital, Pittsburgh
A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)
RecruitingPhase 2/3
- Local Institution - 0360, Pittsburgh
E-Mindfulness Approaches for Living After Breast Cancer
RecruitingPhase 3
- UPMC-Magee Womens Hospital, Pittsburgh
- UPMC-Saint Margaret, Pittsburgh
- UPMC Hillman Cancer Center, Pittsburgh
- and 2 more
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
RecruitingPhase 1/2
- Allegheny Health Network, Pittsburgh
Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors
RecruitingPhase 1
- UPMC Hillman Cancer Center, Pittsburgh
TeleHealth Resistance Exercise Intervention to Preserve Dose Intensity and Vitality in Elder Breast Cancer Patients
Recruiting
- University of Pittsburgh, Pittsburgh
Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors
RecruitingPhase 1
- University of Pittsburg Medical Center (UPCM), Pittsburgh
Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation
RecruitingPhase 1
- UPMC Hillman Cancer Center, Pittsburgh
Proteomics and Radiomics Research of Breast Cancer Markers in Tissue, Interstitial Fluid and Serum
RecruitingObservational study
- UPMC St. Margaret, Pittsburgh
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
RecruitingPhase 3
- Allegheny General Hospital, Pittsburgh
- West Penn Hospital, Pittsburgh
- Jefferson Hospital, Jefferson Hills · 11 mi away
- and 3 more
A Study for CTC Expression and cfDNA/RNA Assessment in Metastatic Breast Cancer Patients
RecruitingObservational study
- UPMC Magee Womens Hospital, Pittsburgh
The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study
RecruitingObservational study
- Allegheny Health Network, Pittsburgh
EXERT-BCH Exercise Regimen to Improve Muscle Mass After Treatment of Breast Cancer
Recruiting
- Allegheny General Hospital, Pittsburgh
Resistance Training and Post Workout Protein to Improve Body Composition During Neoadjuvant Chemotherapy for Breast Cancer
Recruiting
- Allegheny General Hospital, Pittsburgh
EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)
RecruitingObservational study
- UPMC Magee - Womens Hospital, Pittsburgh
The Cancer of the Pancreas Screening-5 CAPS5)Study
RecruitingPhase 3
- University of Pittsburgh, Pittsburgh
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
RecruitingObservational study
- Allegheny Health Network, Pittsburgh
- University of Pittsburgh Medical Centers, Pittsburgh
About Breast Cancer
Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.
More about Breast Cancer on MedlinePlus
Breast Cancer trials in other cities
- New York City, NY136 studies
- Houston, TX126 studies
- Boston, MA112 studies
- Nashville, TN81 studies
- Los Angeles, CA73 studies
- Edison, NJ68 studies
- St. Louis, MO64 studies
- Queens, NY64 studies
- Durham, NC64 studies
- Chicago, IL59 studies
- Philadelphia, PA56 studies
- Dallas, TX55 studies
Other studies in Pittsburgh
- Non-Small Cell Lung Cancer48 studies
- Cancer (all types)41 studies
- Colorectal Cancer32 studies
- Metastatic Cancer31 studies
- Melanoma31 studies
- Ovarian Cancer30 studies
- Endometrial Cancer23 studies
- Prostate Cancer23 studies
- Lung Cancer23 studies
- Head and Neck Squamous Cell Carcinoma22 studies
- Stroke22 studies
- Depression22 studies
From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.