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Breast Cancer clinical trials in Springfield, IL

8 studies for Breast Cancer are looking for participants at sites in and around Springfield (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Clinic, Springfield
  • Springfield Memorial Hospital, Springfield
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

RecruitingPhase 3
  • Simmons Cancer Institute at SIU, Springfield
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336

A Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in Premenopausal Women With Early-stage and Advanced HR+ Breast Cancer

RecruitingPhase 1
  • Springfield Clinic - The Cancer Center, Springfield
Ages 18 to 55 · Women · Updated Sep 9, 2026 · NCT07310420

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

RecruitingPhase 3
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Clinic, Springfield
  • Springfield Memorial Hospital, Springfield
Ages 18 to 60 · Women · Updated Sep 2, 2026 · NCT05879926

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

RecruitingPhase 3
  • Southern Illinois University-Simmons, Springfield
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06072612

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Clinic, Springfield
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Clinic, Springfield
  • Springfield Memorial Hospital, Springfield
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

About Breast Cancer

Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.

More about Breast Cancer on MedlinePlus

Breast Cancer trials in other cities

Other studies in Springfield

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.