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Alzheimer's Disease clinical trials in Durham, NC

8 studies for Alzheimer's Disease are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

ADRC Clinical Cohort (Alzheimer's Disease)

RecruitingObservational studyHealthy volunteers welcome
  • Duke University, Durham
Ages 25 to 80 · All sexes · Updated Sep 3, 2026 · NCT06703541

A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease

RecruitingPhase 1
  • Duke University, Durham
Ages 50 to 85 · All sexes · Updated Aug 24, 2026 · NCT06297590

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

RecruitingPhase 3
  • Duke University Medical Center, Durham
Ages 18 to 75 · All sexes · Updated Aug 4, 2026 · NCT06563895

A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease

RecruitingPhase 2
  • UNC Hosp Invest Drug Serv Pharm, Chapel Hill · 10 mi away
Ages 50 to 85 · All sexes · Updated Jun 26, 2026 · NCT07094516

Olfactory Biopsies

Recruiting
  • Duke University Health Center, Durham
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07021040

A Study of LY4006895 in Healthy Participants With Early Symptomatic Alzheimer's Disease (AD)

RecruitingPhase 1Healthy volunteers welcome
  • Duke Early Phase Research Unit, Durham
Ages 45 to 85 · All sexes · Updated Jun 4, 2026 · NCT06657768

Connect-Home: Alzheimer's Disease and Related Dementias

Recruiting
  • University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Ages 19 and older · All sexes · Updated Mar 30, 2026 · NCT06840587

Retinal Imaging in Neurodegenerative Disease

RecruitingObservational studyHealthy volunteers welcome
  • Duke University Medical Center, Durham
Ages 18 and older · All sexes · Updated Feb 4, 2026 · NCT03233646

About Alzheimer's Disease

Alzheimer's disease is a brain disorder that slowly destroys memory and thinking skills. It's the most common cause of dementia among older adults.

More about Alzheimer's Disease on MedlinePlus

Alzheimer's Disease trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.