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Major Depressive Disorder clinical trials in O'Fallon, MO
9 studies for Major Depressive Disorder are looking for participants at sites in and around O'Fallon (within about 30 miles). Open a study to see who can join and how to contact the study team.
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Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder
RecruitingPhase 3
- Psychiatric Care and Research Center (PCRC), O'Fallon
Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder
RecruitingPhase 3
- Vanda Investigational Site, Saint Charles · 12 mi away
ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response
RecruitingPhase 2
- St. Charles Psychiatric Associates, Inc. dba Midwest Research Group, Saint Charles · 12 mi away
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)
RecruitingPhase 3
- Psychiatric Care and Research Center, O'Fallon
- St. Charles Psychiatric Associates - Midwest Research Group, Saint Charles · 12 mi away
A Study to Evaluate the Maintenance Effect of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
RecruitingPhase 3
- Neurocrine Clinical Site, O'Fallon
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
RecruitingPhase 3
- Neurocrine Clinical Site, O'Fallon
- Neurocrine Clinical Site, Saint Charles · 12 mi away
A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
RecruitingPhase 2
- Midwest Research Group, Saint Charles · 12 mi away
Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)
RecruitingPhase 2
- Autobahn Site #127, Saint Charles · 12 mi away
A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
RecruitingPhase 4
- Clinical Research Site, Saint Charles · 12 mi away
Major Depressive Disorder trials in other cities
- New York City, NY37 studies
- Boston, MA31 studies
- Atlanta, GA25 studies
- Philadelphia, PA23 studies
- Orlando, FL19 studies
- Miami, FL18 studies
- Tampa, FL17 studies
- Chicago, IL17 studies
- Houston, TX16 studies
- San Diego, CA16 studies
- Little Rock, AR14 studies
- Las Vegas, NV13 studies
Other studies in O'Fallon
- Obesity11 studies
- Overweight10 studies
- Prostate Cancer9 studies
- Non-Small Cell Lung Cancer8 studies
- Lung Cancer7 studies
- Acute Myeloid Leukemia6 studies
- Breast Cancer6 studies
- Kidney Cancer (Renal Cell Carcinoma)5 studies
- Melanoma5 studies
- Depression5 studies
- Colorectal Cancer5 studies
- Laryngeal Cancer4 studies
From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.