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Colorectal Cancer clinical trials in Baltimore, MD

31 studies for Colorectal Cancer are looking for participants at sites in and around Baltimore (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Family Communications After Genetic Testing

RecruitingHealthy volunteers welcome
  • Sinai Hospital of Baltimore, Baltimore
  • UM Saint Joseph Medical Center, Towson · 8 mi away
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07143487

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Mercy Medical Center, Baltimore
  • Sinai Hospital of Baltimore, Baltimore
  • MedStar Franklin Square Medical Center/Weinberg Cancer Institute, Baltimore
  • and 2 more
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #14, Baltimore
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Greater Baltimore Medical Center, Baltimore
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

RecruitingPhase 3
  • MedStar Franklin Square Medical Center, Baltimore
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06750094

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

RecruitingPhase 1
  • United Theranostics, Glen Burnie · 9 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213791

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

RecruitingPhase 1/2
  • The Sidney Kimmel Comprehensive Cancer Center at John Hopkins, Baltimore
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06445062

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

RecruitingPhase 1
  • Johns Hopkins, Baltimore
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07349537

SKL35501 With SKL35502 Imaging in Adults With NTSR1 Positive Advanced Solid Tumors

RecruitingPhase 1
  • United Theranostics, Glen Burnie · 9 mi away
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT07812805

Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer

RecruitingPhase 1/2
  • University of Maryland/Greenebaum Cancer Center, Baltimore
  • Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07147231

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Clinical Study Site, Baltimore
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07228832

A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer

RecruitingPhase 2
  • Research Site, Baltimore
Ages 18 to 130 · All sexes · Updated Aug 18, 2026 · NCT06792695

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Johns Hopkins University, The Sidney Kimmel Comprehensive Cancer Center, Baltimore
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer

RecruitingPhase 1
  • Sidney Kimmel Comprehensive Cancer Center, Baltimore
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT06411691

A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

RecruitingPhase 1
  • Sidney Kimmel Comprehensive Cancer Center At Johns Hopkins, Baltimore
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT06179160

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

RecruitingPhase 1
  • Sidney Kimmel Comprehensive Cancer at Johns Hopkins, Baltimore
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT06131840

Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or REGN7075 in Locally Advanced Rectal Cancer

RecruitingPhase 2
  • Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore
Ages 18 and older · All sexes · Updated Jul 21, 2026 · NCT07281768

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

RecruitingPhase 4
  • Mercy Medical Center, Baltimore
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT06562543

Anastomotic Safety and Surveillance Using Real-time Enhanced Sensing Using xBar

Recruiting
  • Johns Hopkins University, Baltimore
Ages 21 and older · All sexes · Updated Jun 16, 2026 · NCT07337590

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

RecruitingPhase 1
  • Advanced Molecular Imaging and Therapy, Glen Burnie · 9 mi away
  • United Theranostics - Chesapeake, Glen Burnie · 9 mi away
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT05283330

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • Johns Hopkins University, Baltimore
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies

RecruitingPhase 1/2
  • Johns Hopkins Hospital, Baltimore
Ages 18 and older · All sexes · Updated May 28, 2026 · NCT07223047

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • Johns Hopkins University, Baltimore
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally Advanced MSI-H Colorectal Cancer

RecruitingPhase 2
  • Johns Hopkins SKCCC, Baltimore
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06205836

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

RecruitingPhase 1/2
  • Johns Hopkins University, Baltimore
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT07020221

An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.

RecruitingPhase 2
  • NGM Clinical Study Site, Baltimore
Ages 18 and older · All sexes · Updated Apr 1, 2026 · NCT07033026

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • University of Maryland/Greenebaum Cancer Center, Baltimore
  • Sinai Hospital of Baltimore, Baltimore
  • UM Saint Joseph Medical Center, Towson · 8 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

About Colorectal Cancer

Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.

More about Colorectal Cancer on MedlinePlus

Colorectal Cancer trials in other cities

Other studies in Baltimore

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.