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Sickle Cell Disease clinical trials in Memphis, TN

18 studies for Sickle Cell Disease are looking for participants at sites in and around Memphis (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

RecruitingPhase 3
  • University of Tennessee Health Science Center, Memphis
  • St. Jude Children's Res Hosp, Memphis
Ages 12 and older · All sexes · Updated Sep 17, 2026 · NCT06612268

Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell Disease

RecruitingPhase 1
  • St. Jude Children's Research Hospital, Memphis
Ages 8 to 17 · All sexes · Updated Sep 9, 2026 · NCT07226219

SCD Stem Cell Mobilization and Apheresis Using Motixafortide

RecruitingPhase 1
  • St. Jude Children's Research Hospital, Memphis
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06442761

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

RecruitingObservational study
  • St. Jude Children's Research Hospital, Memphis
All ages · All sexes · Updated Aug 17, 2026 · NCT04398628

Gene Therapy Communication: Use of a Needs Assessment to Drive Decision-AIDS for Gene Therapy for Rare Diseases (GENETX)

RecruitingObservational studyHealthy volunteers welcome
  • St. Jude Children's Research Hospital, Memphis
Ages 8 and older · All sexes · Updated Aug 10, 2026 · NCT05810181

Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease

RecruitingPhase 2
  • St Jude Children's Research Hospital, Memphis
Up to age 22 · All sexes · Updated Jul 23, 2026 · NCT07616154

Peripheral Arterial Tonometry and Neurocognition in Sickle Cell Disease

RecruitingObservational study
  • St. Jude Children's Research Hospital, Memphis
Ages 12 to 25 · All sexes · Updated Jun 29, 2026 · NCT06477289

Investigation of the Genetics of Hematologic Diseases

RecruitingObservational study
  • St. Jude Children's Research Hospital, Memphis
All ages · All sexes · Updated Jun 9, 2026 · NCT02720679

Sickle Cell Clinical Research and Intervention Program

RecruitingObservational study
  • Regional One Health, Diggs-Kraus Sickle Cell Center, Memphis
  • Methodist Adult Comprehensive Sickle Cell Center, Memphis
  • St. Jude Children's Research Hospital, Memphis
All ages · All sexes · Updated Jun 4, 2026 · NCT02098863

Functional Ovarian Reserve in Sickle Cell Disease

RecruitingObservational studyHealthy volunteers welcome
  • St. Jude Children's Research Hospital, Memphis
Ages 10 to 18 · Women · Updated Jun 4, 2026 · NCT07392216

Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

RecruitingObservational study
  • St Jude Children Hospital (NT-DMT), Memphis
  • St. Jude Children's Research Hospital (MRD-HCT), Memphis
Ages 3 to 20 · All sexes · Updated Jun 4, 2026 · NCT06941389

Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease

Recruiting
  • St. Jude Children's Research Hospital, Memphis
Ages 6 to 25 · All sexes · Updated May 18, 2026 · NCT03353584

Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle Cell Disease Using PET

RecruitingPhase 2Healthy volunteers welcome
  • St. Jude Children's Research Hospital, Memphis
Ages 18 to 21 · All sexes · Updated May 6, 2026 · NCT05583721

Gene Editing For Sickle Cell Disease

RecruitingPhase 1
  • St. Jude Children's Research Hospital, Memphis
Ages 18 to 24 · All sexes · Updated May 5, 2026 · NCT06506461

Sickle Cell Disease and the Genomic and Gene Therapy Needs of Stakeholders

RecruitingObservational studyHealthy volunteers welcome
  • St. Jude Children's Research Hospital, Memphis
Ages 13 and older · All sexes · Updated May 1, 2026 · NCT04416178

School Readiness Intervention for Preschool Children With Sickle Cell Disease

Recruiting
  • St. Jude Children's Research Hospital, Memphis
42 Months – 78 Months · All sexes · Updated Apr 24, 2026 · NCT06367192

A Long-term Follow-up Study in Patients Who Received BEAM-101

RecruitingObservational study
  • St. Jude Children's Research Hospital, Memphis
Ages 14 to 37 · All sexes · Updated Jan 28, 2026 · NCT07373639

Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease

RecruitingObservational study
  • University of Tennessee at Memphis, Memphis
Ages 18 and older · All sexes · Updated Jun 22, 2025 · NCT06385886

About Sickle Cell Disease

Sickle cell disease is a group of inherited disorders that affect your red blood cells. It can cause pain, anemia, and other problems. Learn about treatments.

More about Sickle Cell Disease on MedlinePlus

Sickle Cell Disease trials in other cities

Other studies in Memphis

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.