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Cardiovascular Disease clinical trials in Durham, NC

17 studies for Cardiovascular Disease are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

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ELEVATE-HFpEF Clinical Study

Recruiting
  • Duke University Medical Center, Durham
Ages 40 and older · All sexes · Updated Oct 2, 2026 · NCT06678841

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

RecruitingPhase 3
  • The University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07064473

Product Surveillance Registry

RecruitingObservational study
  • Durham, Durham
  • Chapel Hill, Chapel Hill · 10 mi away
All ages · All sexes · Updated Sep 18, 2026 · NCT01524276

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

RecruitingPhase 3
  • Clinical Trial Site, Durham
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07181109

Pharmacologic Therapies to Mitigate Radiation- Associated Heart Disease

RecruitingPhase 2
  • Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07685938

Zenith® Fenestrated+ Clinical Study

Recruiting
  • University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT04875429

Observational Pharmaco-Epidemiology Research & Analysis

RecruitingObservational studyHealthy volunteers welcome
  • Epividian, Durham
Ages 0 and older · All sexes · Updated Sep 11, 2026 · NCT03813862

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

Recruiting
  • Duke University, Durham
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • PREVENTABLE Tele-Site, Durham
  • Duke University, Durham
  • University of North Carolina, Chapel Hill · 10 mi away
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

RecruitingPhase 3
  • Research Site, Durham
  • Research Site, Durham
  • Research Site, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

RecruitingPhase 3
  • Duke University Health System, Durham
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012

Global Paradise System US Post Approval Study

RecruitingObservational study
  • Durham VA Health System, Durham
  • University of North Carolina at Chapel Hill School of Medicine, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06297291

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
  • UNC Medical Center, Durham
  • Duke University, Durham
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

SPYRAL GEMINI Pilot Study

Recruiting
  • University of North Carolina (UNC) Memorial Hospital, Chapel Hill · 10 mi away
Ages 18 to 80 · All sexes · Updated Jun 24, 2026 · NCT06907147

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Recruiting
  • University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

PKP2-ACM Natural History Study

RecruitingObservational study
  • Duke University, Durham
Ages 12 and older · All sexes · Updated Feb 27, 2026 · NCT06644742

Beta-Blocker Influences on Inflammatory and Neural Responses to Stress

RecruitingPhase 4Healthy volunteers welcome
  • Social Neuroscience and Health Laboratory, Chapel Hill · 10 mi away
Ages 18 to 30 · All sexes · Updated Oct 29, 2025 · NCT06263452

Cardiovascular Disease trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.