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Prostate Cancer clinical trials in Baltimore, MD

43 studies for Prostate Cancer are looking for participants at sites in and around Baltimore (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

RecruitingPhase 3
  • Maryland Proton Treatment Center, Baltimore
  • University of Maryland/Greenebaum Cancer Center, Baltimore
  • UM Baltimore Washington Medical Center/Tate Cancer Center, Glen Burnie · 9 mi away
  • and 1 more
Ages 18 and older · Men · Updated Oct 2, 2026 · NCT07200830

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Mercy Medical Center, Baltimore
  • Sinai Hospital of Baltimore, Baltimore
  • MedStar Franklin Square Medical Center/Weinberg Cancer Institute, Baltimore
  • and 2 more
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • Johns Hopkins University, Baltimore
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

Prostate Cancer Risk Identification in a Multi-Ethnic Cohort: a Prospective US-based Multi-center Validation Study of Proclarix

RecruitingObservational study
  • Chesapeake Urology Associates, Towson · 8 mi away
Ages 40 to 75 · Men · Updated Sep 28, 2026 · NCT07543757

Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer

RecruitingPhase 1
  • University of Maryland, Greenebaum Comprehensive Cancer Center, Baltimore
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06801236

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

RecruitingPhase 3
  • Baltimore Veterans Affairs Medical Center ( Site 0069), Baltimore
  • Greenebaum Comprehensive Cancer Center ( Site 0049), Baltimore
  • Chesapeake Urology ( Site 0009), Towson · 8 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06136650

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

RecruitingPhase 3
  • University of Maryland Greenebaum Cancer Center, Baltimore
  • Johns Hopkins Hospital Sidney Kimmell Comprehensive Cancer Center, Baltimore
Ages 18 and older · Men · Updated Sep 22, 2026 · NCT07213674

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

RecruitingPhase 3
  • Research Site, Towson · 8 mi away
Ages 18 and older · Men · Updated Sep 18, 2026 · NCT06952803

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

RecruitingPhase 3
  • Greenebaum Comprehensive Cancer Center ( Site 0021), Baltimore
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT06925737

PROMISE Registry: A Prostate Cancer Registry of Outcomes and Germline Mutations for Improved Survival and Treatment Effectiveness

RecruitingObservational study
  • Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore
Ages 18 and older · Men · Updated Sep 15, 2026 · NCT04995198

A Biomarker Study in Men With Localized Prostate Cancer Treated With Aglatimagene Besadenovec

RecruitingPhase 2
  • Chesapeake Urology Research Associates, Towson · 8 mi away
Ages 18 and older · Men · Updated Sep 15, 2026 · NCT07332000

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

Recruiting
  • Anne Arundel Urology, Annapolis · 22 mi away
Ages 18 and older · Men · Updated Sep 14, 2026 · NCT06511141

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

RecruitingPhase 3
  • Maryland Proton Treatment Center, Baltimore
  • University of Maryland/Greenebaum Cancer Center, Baltimore
  • Veterans Administration Medical Center-Baltimore, Baltimore
  • and 4 more
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213

Patient Navigation Program to Improve Clinical Trial Enrollment in Cancer Patients

Recruiting
  • Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06138067

Transrectal Ultrasound Robot-Assisted Prostate Biopsy

Recruiting
  • Johns Hopkins Hospital, Baltimore
Ages 45 to 75 · Men · Updated Aug 26, 2026 · NCT02871726

Study of Oral MRT-2359 With Apalutamide in Prostate Cancer

RecruitingPhase 2
  • University of Maryland Greenebaum Cancer Center, Baltimore
Ages 18 and older · Men · Updated Aug 24, 2026 · NCT07745361

A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

RecruitingPhase 1/2
  • Johns Hopkins Hospital, Baltimore
Ages 18 and older · Men · Updated Aug 20, 2026 · NCT06785636

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

RecruitingPhase 3
  • Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore
Ages 18 and older · Men · Updated Aug 19, 2026 · NCT04423211

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Johns Hopkins University, The Sidney Kimmel Comprehensive Cancer Center, Baltimore
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

RecruitingPhase 1
  • University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore
Ages 18 to 100 · Men · Updated Aug 13, 2026 · NCT05519449

Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer

RecruitingObservational study
  • Johns Hopkins University, Baltimore
Ages 18 and older · Men · Updated Aug 12, 2026 · NCT04489719

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

RecruitingPhase 3
  • Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore
Ages 18 and older · Men · Updated Jul 14, 2026 · NCT06592924

Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells

RecruitingPhase 2
  • Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore
Ages 18 and older · Men · Updated Jul 14, 2026 · NCT05691465

Study of ORIC-944 in Patients With Metastatic Prostate Cancer

RecruitingPhase 1
  • Marlene & Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore
Ages 18 and older · Men · Updated Jul 9, 2026 · NCT05413421

7-Days Water-Only Fasting or Ketone Supplementation Trial in Prostate Cancer

Recruiting
  • Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore
Ages 18 and older · Men · Updated Jun 30, 2026 · NCT06826924

The COSMYC Trial (COmbined Suppression of MYC)

RecruitingPhase 2
  • Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore
Ages 18 and older · Men · Updated Jun 18, 2026 · NCT06922318

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

RecruitingPhase 1
  • Advanced Molecular Imaging and Therapy, Glen Burnie · 9 mi away
  • United Theranostics - Chesapeake, Glen Burnie · 9 mi away
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT05283330

TERPS Trial for de Novo Oligometastic Prostate Cancer

RecruitingPhase 2
  • Maryland Proton Treatment Center, Baltimore
  • UMMC, Baltimore
  • Baltimore Washington Medical Center, Glen Burnie · 9 mi away
  • and 1 more
Ages 18 and older · Men · Updated Jun 3, 2026 · NCT05223803

International Registry for Men With Advanced Prostate Cancer (IRONMAN)

RecruitingObservational study
  • Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore
Ages 21 and older · Men · Updated May 22, 2026 · NCT03151629

Clinical Trial of Approaches to Prostate Cancer Surgery

Recruiting
  • Johns Hopkins University, Baltimore
Ages 40 to 80 · Men · Updated Apr 22, 2026 · NCT05155501

Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

RecruitingPhase 2/3
  • Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD, Baltimore
Ages 18 and older · Men · Updated Apr 8, 2026 · NCT04787744

SPECT Imaging for Pharmacokinetics and dosimEtry Towards TREATment Optimization

RecruitingObservational study
  • Johns Hopkins University, Baltimore
Ages 18 to 100 · All sexes · Updated Mar 30, 2026 · NCT06389097

Supraphysiologic Testosterone Priming Induces Darolutamide Extended Response

RecruitingPhase 2
  • Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore
Ages 18 and older · Men · Updated Mar 11, 2026 · NCT07142551

Trial Targeting Gut Bacterial Androgen Production to Reverse Therapeutic Resistance to Abiraterone in Patients With Metastatic Prostate Cancer

RecruitingPhase 2
  • Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore
Ages 18 and older · Men · Updated Feb 19, 2026 · NCT06616597

Image-guided Focal Brachytherapy Utilizing Combined 18F-DCFPyl PET/CT

RecruitingEarly phase 1
  • SKCCC at Johns Hopkins, Baltimore
Ages 18 to 100 · Men · Updated Feb 13, 2026 · NCT03861676

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

RecruitingPhase 1
  • Johns Hopkins - Sidney Kimmel Comprehensive Cancer Center, Baltimore
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863

A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

RecruitingPhase 1
  • Chesapeake Urology, Towson · 8 mi away
Ages 18 and older · Men · Updated Feb 4, 2026 · NCT04729114

Physician- and Patient-based Barriers to NGS Testing

Recruiting
  • Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore
Ages 18 and older · Men · Updated Feb 3, 2026 · NCT07209176

Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer

RecruitingPhase 2
  • Johns Hopkins University: Sidney Kimmel Comprehensive Cancer Center, Baltimore
Ages 18 and older · Men · Updated Jan 14, 2026 · NCT06059118

Robot-Assisted Prostate Biopsy With a Novel Ultrasound Probe

RecruitingPhase 1
  • Johns Hopkins Hospital, Baltimore
Ages 40 to 75 · Men · Updated Dec 8, 2025 · NCT07271017

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Baltimore
  • Massive Bio SYNERGY-AI site, Towson · 8 mi away
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Exercise in Prostate Cancer

Recruiting
  • Johns Hopkins University, Baltimore
Ages 18 to 80 · All sexes · Updated Oct 20, 2025 · NCT06165302

A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

RecruitingPhase 1/2
  • Johns Hopkins, Baltimore
Ages 18 and older · All sexes · Updated May 1, 2025 · NCT04503265

About Prostate Cancer

Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.

More about Prostate Cancer on MedlinePlus

Prostate Cancer trials in other cities

Other studies in Baltimore

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.