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Alzheimer's Disease clinical trials in Cleveland, OH

6 studies for Alzheimer's Disease are looking for participants at sites in and around Cleveland (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

RecruitingPhase 3
  • Local Institution - 1265, Cleveland
Ages 55 to 90 · All sexes · Updated Sep 22, 2026 · NCT06585787

Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

RecruitingPhase 2
  • Cleveland Clinic, Cleveland
Ages 55 to 90 · All sexes · Updated Sep 1, 2026 · NCT06808984

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

RecruitingPhase 3
  • Cleveland Clinic, Cleveland
Ages 18 to 75 · All sexes · Updated Aug 4, 2026 · NCT06563895

A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)

RecruitingPhase 3
  • Local Institution - 0029, Cleveland
Ages 55 to 90 · All sexes · Updated Jun 30, 2026 · NCT06947941

[18F]PI-2620 Phase 3 Histopathological Study

RecruitingPhase 3
  • Insight Clinical Trials LLC, Beachwood · 10 mi away
Ages 50 and older · All sexes · Updated May 22, 2026 · NCT05641688

Trial-Ready Cohort-Down Syndrome (TRC-DS)

RecruitingObservational study
  • Case Western Reserve University, Beachwood · 10 mi away
Ages 25 to 55 · All sexes · Updated May 18, 2026 · NCT04165109

About Alzheimer's Disease

Alzheimer's disease is a brain disorder that slowly destroys memory and thinking skills. It's the most common cause of dementia among older adults.

More about Alzheimer's Disease on MedlinePlus

Alzheimer's Disease trials in other cities

Other studies in Cleveland

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.