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Cancer (all types) clinical trials in Jacksonville, FL
29 studies for Cancer (all types) are looking for participants at sites in and around Jacksonville (within about 30 miles). Open a study to see who can join and how to contact the study team.
Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →
A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan, Monotherapy or in Combination With Osimertinib, Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer
RecruitingPhase 2/3
- Cancer Specialists of North Florida /ID# 277332, Jacksonville
Registry Study for Radiation Therapy Outcomes
RecruitingObservational study
- Ackerman Cancer Center, Jacksonville
Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
RecruitingObservational study
- Mayo Clinic Jacksonville, Jacksonville
A Study of JNJ-1761981 in Participants With Solid Tumors
RecruitingPhase 1
- Mayo Clinic in Florida, Jacksonville
A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
RecruitingPhase 2/3
- Mayo Clinic Pharmacy, Jacksonville
- Mayo Clinic, Jacksonville
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
RecruitingPhase 2/3
- The Mayo Clinic - Jacksonville, Davis-E, Jacksonville
A Study to Investigate Safety and Effectiveness of Tacabrutideg (BGB-16673) in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies
RecruitingPhase 1/2
- Mayo Clinic Jacksonville, Jacksonville
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
RecruitingPhase 3
- University of Florida - Jacksonville, Jacksonville
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation
RecruitingPhase 3
- Cancer Specialists of North Florida - Southpoint, Jacksonville
A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)
RecruitingObservational study
- Mayo Clinic Florida, Jacksonville
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
RecruitingPhase 3
- Mayo Clinic Florida-Comprehensive Cancer Center, Jacksonville
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer
RecruitingPhase 1
- Mayo Clinic Florida, Jacksonville
Project: Every Child for Younger Patients With Cancer
RecruitingObservational study
- Nemours Children's Clinic-Jacksonville, Jacksonville
FOG-001 in Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
- Mayo Clinic, Jacksonville
A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer
RecruitingPhase 2
- Mayo Clinic in Florida, Jacksonville
A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
RecruitingPhase 2
- Mayo Clinic Hospital Jacksonville /ID# 274472, Jacksonville
A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
RecruitingPhase 1/2
- Mayo Clinic, Jacksonville
A Study of Live Tumor Fragments of Surgical Resections
RecruitingObservational study
- Mayo Clinic in Florida, Jacksonville
A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors
RecruitingPhase 1
- Mayo Clinic Jacksonville, Jacksonville
A Multilevel Approach to Connecting Underrepresented Populations to Clinical Trials
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Florida, Jacksonville
CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)
RecruitingPhase 1/2
- Mayo Clinic, Jacksonville
INTERogating Cancer for Etiology, Prevention and Therapy Navigation
RecruitingObservational study
- Mayo Clinic in Florida, Jacksonville
Multi-Cancer Detection Observational Cohort Study
RecruitingObservational studyHealthy volunteers welcome
- Mayo Clinic in Florida, Jacksonville
Virtual Reality Intervention to Improve Psychological Symptom Burden for Cancer Patients Undergoing Treatment
Recruiting
- Mayo Clinic in Florida, Jacksonville
TEMPUS ARIES: A Biobank Registry Platform Study in Oncology
RecruitingObservational study
- Cancer Specialists of North Florida, Jacksonville
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
RecruitingObservational study
- Massive Bio SYNERGY-AI site, Jacksonville
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
RecruitingPhase 1/2
- Mayo Clinic, Jacksonville
Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
Recruiting
- Baptist MD Anderson Cancer Center, Jacksonville
- Mayo Clinic in Florida, Jacksonville
Registry Study for Proton Therapy Clinical Outcomes and Long-Term Follow-up
RecruitingObservational study
- Ackerman Cancer Center, Jacksonville
About Cancer (all types)
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More about Cancer (all types) on MedlinePlus
Cancer (all types) trials in other cities
- Houston, TX121 studies
- New York City, NY110 studies
- Boston, MA86 studies
- Los Angeles, CA73 studies
- Nashville, TN65 studies
- Philadelphia, PA59 studies
- Durham, NC58 studies
- Washington, DC58 studies
- Chicago, IL51 studies
- Seattle, WA49 studies
- Atlanta, GA49 studies
- Arlington, VA48 studies
Other studies in Jacksonville
- Breast Cancer40 studies
- Non-Small Cell Lung Cancer39 studies
- Metastatic Cancer28 studies
- Colorectal Cancer27 studies
- Prostate Cancer26 studies
- Obesity25 studies
- Heart Failure21 studies
- Pancreatic Cancer20 studies
- Overweight19 studies
- Multiple Myeloma18 studies
- Lung Cancer17 studies
- Stroke16 studies
From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.