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Glioblastoma clinical trials in St. Louis, MO

12 studies for Glioblastoma are looking for participants at sites in and around St. Louis (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

RecruitingPhase 2
  • Washington University School of Medicine Siteman Cancer Center, St Louis
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07326566

A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM

RecruitingPhase 1
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05303467

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

RecruitingPhase 1/2
  • Washington University School of Medicine in St. Louis, St Louis
Up to age 25 · All sexes · Updated Sep 25, 2026 · NCT04094610

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

RecruitingPhase 3
  • Washington University School of Medicine, St Louis
  • Siteman Cancer Center-South County, St Louis
  • Siteman Cancer Center at Christian Hospital, St Louis
  • and 5 more
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT07452458

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

RecruitingPhase 1
  • Siteman Cancer Center at Washington University, St Louis
36 Months – 22 Years · All sexes · Updated Sep 4, 2026 · NCT03911388

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

RecruitingPhase 3
  • Washington University, St Louis
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT05303519

Neurosurgical Neuronavigation Using Resting State MRI and Machine Learning

RecruitingObservational study
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Jun 30, 2026 · NCT05864976

Safety and Efficacy of CTX-009 With or Without CTX-471 for Recurrent Glioblastoma

RecruitingPhase 1/2
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Jun 22, 2026 · NCT07392957

Neoadjuvant Chemoradiotherapy With or Without Concurrent Azeliragon in Patients With Newly Diagnosed Glioblastoma

RecruitingEarly phase 1
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated May 29, 2026 · NCT06831526

Sonobiopsy for Noninvasive and Sensitive Detection of Glioblastoma

Recruiting
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated May 14, 2026 · NCT05281731

Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1

RecruitingPhase 2
  • Washington University School of Medicine, St Louis
Ages 18 and older · All sexes · Updated Apr 21, 2026 · NCT07462507

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, St Louis
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Glioblastoma trials in other cities

Other studies in St. Louis

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.