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Multiple Myeloma clinical trials in Philadelphia, PA

16 studies for Multiple Myeloma are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis

RecruitingPhase 1
  • University of Pennsylvania Division of Hematology Oncology Perelman Center for Advanced Medicine, Philadelphia
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05652335

A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 3
  • Thomas Jefferson University Hospital, Philadelphia
  • Fox Chase Cancer Center, Philadelphia
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07258511

A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

RecruitingPhase 4
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05201781

A Study of mRNA-2808 in Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 1/2
  • Penn Medicine, Philadelphia
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07116616

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

RecruitingPhase 2
  • Fox Chase Cancer Center, Philadelphia
Ages 12 and older · All sexes · Updated Sep 22, 2026 · NCT02693535

Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

RecruitingPhase 2
  • Sidney Kimmel Cancer Center - Jefferson Health, Philadelphia
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06297226

AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Multiple Myeloma

RecruitingPhase 1/2
  • Research Site, Philadelphia
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT06106945

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

RecruitingPhase 3
  • Thomas Jefferson University Hospital, Philadelphia
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT04566328

A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma

RecruitingPhase 1
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT05651932

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

RecruitingPhase 1/2
  • Penn Medicine - Abramson Cancer Center Perelman, Philadelphia
Ages 18 and older · All sexes · Updated Jun 24, 2026 · NCT04068597

Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma

Recruiting
  • University of Pennsylvania/Abramson Cancer Center, Philadelphia
Ages 18 and older · All sexes · Updated Jun 5, 2026 · NCT03858205

Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation

RecruitingPhase 3
  • Abramson Cancer Center University of Pennsylvania Medical Center, Philadelphia
  • Fox Chase Cancer Center, Philadelphia
Ages 18 and older · All sexes · Updated Jun 4, 2026 · NCT05243797

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

RecruitingPhase 1/2
  • Sidney Kimmel Comprehensive Cancer Center, Philadelphia
Ages 12 and older · All sexes · Updated Mar 24, 2026 · NCT04988555

Mozobil for Autologous Hematopoietic Stem Cell Transplantation

RecruitingPhase 2
  • Thomas Jefferson University Hospital, Philadelphia
Ages 18 and older · All sexes · Updated Nov 28, 2025 · NCT07188090

Limited-duration Teclistamab

RecruitingPhase 2
  • Abramson Cancer Center at University of Pennsylvania, Philadelphia
  • Thomas Jefferson University, Honickman Center, Philadelphia
Ages 18 and older · All sexes · Updated Oct 1, 2025 · NCT05932680

About Multiple Myeloma

Multiple myeloma is a cancer that begins in plasma cells, a type of white blood cell. Discover symptoms, diagnostic tests, and treatments for myeloma.

More about Multiple Myeloma on MedlinePlus

Multiple Myeloma trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.