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Epilepsy clinical trials in Chicago, IL

5 studies for Epilepsy are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study

RecruitingPhase 2
  • Lurie Children's Hospital of Chicago, Chicago
1 Day – 6 Months · All sexes · Updated Oct 2, 2026 · NCT05104983

Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures

RecruitingPhase 3
  • Re:Cognition Health-Chicago, Chicago
Ages 18 to 75 · All sexes · Updated Sep 2, 2026 · NCT07594119

Comparative Effectiveness of Palliative Surgery Versus Additional Anti-Seizure Medications for Lennox-Gastaut Syndrome

RecruitingObservational study
  • Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
Up to age 26 · All sexes · Updated Aug 6, 2026 · NCT05374824

A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety

RecruitingPhase 3
  • Praxis Research Site, Chicago
1 Day – 18 Years · All sexes · Updated Aug 3, 2026 · NCT07019922

Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))

RecruitingPhase 3
  • Rush University Medical Center, Chicago
  • University of Chicago, Chicago
Ages 18 to 75 · All sexes · Updated Jun 9, 2026 · NCT05135091

About Epilepsy

Epilepsy is a brain disorder that causes people to have seizures. The seizures may be mild or severe. Learn about causes, diagnosis, and treatment.

More about Epilepsy on MedlinePlus

Epilepsy trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.