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Alzheimer's Disease clinical trials recruiting in the U.S.
236 studies for Alzheimer's Disease are recruiting participants at sites across the United States.
Alzheimer's disease is a brain disorder that slowly destroys memory and thinking skills. It's the most common cause of dementia among older adults.
Cities with the most studies
- Boston, MA26 studies
- Orlando, FL25 studies
- St. Louis, MO22 studies
- New York City, NY21 studies
- Miami, FL20 studies
- Tampa, FL17 studies
- Atlanta, GA16 studies
- Philadelphia, PA15 studies
- Phoenix, AZ15 studies
- The Villages, FL15 studies
- Los Angeles, CA14 studies
- Indianapolis, IN14 studies
- West Palm Beach, FL13 studies
- Houston, TX12 studies
- San Diego, CA12 studies
- Dallas, TX12 studies
- Newton, MA12 studies
- Irvine, CA11 studies
- Chicago, IL11 studies
- Pittsburgh, PA10 studies
- Baltimore, MD10 studies
- Seattle, WA10 studies
- San Antonio, TX10 studies
- Portland, OR10 studies
- Austin, TX10 studies
- Nashville, TN10 studies
- Deltona, FL10 studies
- Cape Coral, FL9 studies
- Toms River, NJ9 studies
- Jacksonville, FL8 studies
- Boca Raton, FL8 studies
- New Haven, CT8 studies
- Las Vegas, NV8 studies
- Durham, NC8 studies
- Providence, RI8 studies
- Farmington Hills, MI8 studies
- Charlotte, NC8 studies
- Queens, NY8 studies
- Long Beach, CA8 studies
- Orange, CA7 studies
By state
- Alabama8 studies
- Arizona23 studies
- California48 studies
- Colorado13 studies
- Connecticut12 studies
- District of Columbia5 studies
- Florida51 studies
- Georgia24 studies
- Hawaii3 studies
- Illinois19 studies
- Indiana16 studies
- Kansas7 studies
- Louisiana8 studies
- Maryland13 studies
- Massachusetts45 studies
- Michigan15 studies
- Minnesota9 studies
- Mississippi5 studies
- Missouri28 studies
- Nevada8 studies
- New Jersey25 studies
- New York37 studies
- North Carolina21 studies
- Ohio17 studies
- Oklahoma6 studies
- Oregon11 studies
- Pennsylvania24 studies
- Rhode Island8 studies
- South Carolina4 studies
- Tennessee16 studies
- Texas40 studies
- Utah5 studies
- Virginia12 studies
- Washington17 studies
- Wisconsin6 studies
Recently updated studies
Amyloid PET Imaging in the Baltimore Longitudinal Study of Aging
RecruitingObservational studyHealthy volunteers welcome
Ages 55 to 110 · All sexes · Updated Oct 2, 2026 · NCT07099053NON-INVASIVE BRAIN STIMULATION FOR MEMORY LOSS IN EARLY ALZHEIMER'S DISEASE
Recruiting
Ages 55 to 90 · All sexes · Updated Oct 1, 2026 · NCT07667478DUVAX: A Phase 1 Alzheimer's Vaccine Study Targeting Amyloid-Beta and Tau
RecruitingPhase 1Healthy volunteers welcome
Ages 40 to 65 · All sexes · Updated Sep 30, 2026 · NCT07142278A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
RecruitingPhase 2
Ages 55 to 90 · All sexes · Updated Sep 30, 2026 · NCT06887192A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease
RecruitingPhase 2
Ages 55 and older · All sexes · Updated Sep 29, 2026 · NCT06540833The Gut - PRO Study
RecruitingPhase 1Healthy volunteers welcome
Ages 60 and older · All sexes · Updated Sep 29, 2026 · NCT07413744Randomized Study to Evaluate the Effect of Obicetrapib in Participants With Preclinical Alzheimer's Disease
RecruitingPhase 2
Ages 55 to 85 · All sexes · Updated Sep 28, 2026 · NCT07794670A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
RecruitingPhase 3
Ages 55 to 90 · All sexes · Updated Sep 28, 2026 · NCT06937229Dominantly Inherited Alzheimer Network (DIAN)
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT00869817A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)
RecruitingPhase 4
Ages 50 and older · All sexes · Updated Sep 25, 2026 · NCT07633470A Study to Evaluate the Drug Levels, Absolute Bioavailability, Safety, Tolerability, and Immunogenicity of Single-Dose of BMS-986446 in Healthy Adults After Single-dose Administration, and Participants With Early Alzheimer's Disease After Multiple Dose Administration
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 80 · All sexes · Updated Sep 24, 2026 · NCT07780383A Study of LY3439539 in Participants With Alzheimer's Disease
RecruitingPhase 1
Ages 50 to 85 · All sexes · Updated Sep 24, 2026 · NCT07598370Interleukine-2 (IL-2) Plus Semaglutide in Alzheimer's Disease
RecruitingPhase 1/2
Ages 50 to 86 · All sexes · Updated Sep 23, 2026 · NCT07651319Combating Alzheimer's Through Sleep and Exercise
RecruitingHealthy volunteers welcome
Ages 55 to 80 · All sexes · Updated Sep 23, 2026 · NCT04855630Improving Memory in Alzheimer's Disease With Noninvasive Brain Stimulation
RecruitingHealthy volunteers welcome
Ages 50 to 100 · All sexes · Updated Sep 23, 2026 · NCT06094192A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
RecruitingPhase 2
Ages 55 to 85 · All sexes · Updated Sep 22, 2026 · NCT07589595A Study to Investigate the Safety and Effectiveness of SAR448851 in Participants With Early Alzheimer's Disease
RecruitingPhase 2
Ages 55 to 85 · All sexes · Updated Sep 22, 2026 · NCT07688213A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
RecruitingPhase 3
Ages 55 to 90 · All sexes · Updated Sep 22, 2026 · NCT06585787Predicting Pre-dementia
RecruitingObservational studyHealthy volunteers welcome
Ages 55 and older · All sexes · Updated Sep 22, 2026 · NCT07516119Comparison of Two Group Wellness Interventions for Individuals With Neurologic Conditions and Their Support Persons
Recruiting
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05048966Microbiome in Aging of Gut and Brain
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07799402Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
RecruitingPhase 2
Ages 55 to 80 · All sexes · Updated Sep 21, 2026 · NCT06847321Music for Pain and Dementia
Recruiting
Ages 50 to 80 · All sexes · Updated Sep 21, 2026 · NCT07602283PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using [18F]-PI-2620
RecruitingPhase 3Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05456503Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
RecruitingPhase 3
Ages 50 to 90 · All sexes · Updated Sep 21, 2026 · NCT07177352From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.