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Colorectal Cancer clinical trials in Lexington, KY

11 studies for Colorectal Cancer are looking for participants at sites in and around Lexington (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Family Communications After Genetic Testing

RecruitingHealthy volunteers welcome
  • CommonSpirit Saint Joseph Hospital - Lexington, Lexington
  • Saint Joseph Radiation Oncology Resource Center, Lexington
  • CommonSpirit Saint Joseph Medical Center - East Lexington, Lexington
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07143487

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • CommonSpirit Saint Joseph Hospital - Lexington, Lexington
  • Saint Joseph Radiation Oncology Resource Center, Lexington
  • CommonSpirit Saint Joseph Medical Center - East Lexington, Lexington
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Baptist Health Lexington, Lexington
  • Baptist Health Richmond, Lexington
  • Baptist Health Hamburg, Lexington
  • and 3 more
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

RecruitingPhase 3
  • University of Kentucky/Markey Cancer Center, Lexington
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT05863195

Lead-212 PSV359 Therapy for Patients With Solid Tumors

RecruitingPhase 1/2
  • University of Kentucky, Lexington
Ages 18 to 90 · All sexes · Updated Jul 6, 2026 · NCT06710756

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

RecruitingPhase 1
  • UK Markey Cancer Center, Lexington
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT05283330

Flat Dose vs. Weight-based IP Chemotherapy for CRS/HIPEC

RecruitingPhase 2
  • University of Kentucky, Lexington
Ages 18 and older · All sexes · Updated Apr 1, 2026 · NCT04779554

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

RecruitingPhase 3Healthy volunteers welcome
  • Saint Joseph Hospital, Lexington
  • Saint Joseph Radiation Oncology Resource Center, Lexington
  • Saint Joseph Hospital East, Lexington
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT07018869

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Saint Joseph Hospital East, Lexington
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Baptist Lexington, Lexington
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

GENOCARE: A Prospective, Randomized Clinical Trial of Genotype-Guided Dosing Versus Usual Care

Recruiting
  • University of Kentucky, Lexington
Ages 18 and older · All sexes · Updated Dec 16, 2025 · NCT05391126

About Colorectal Cancer

Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.

More about Colorectal Cancer on MedlinePlus

Colorectal Cancer trials in other cities

Other studies in Lexington

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.