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Cystic Fibrosis clinical trials in Philadelphia, PA

15 studies for Cystic Fibrosis are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Genetics of Insulin and Incretins in Cystic Fibrosis

RecruitingObservational study
  • The Children's Hopsital of Philadelphia, Philadelphia
  • The University of Pennsylvania, Philadelphia
Ages 2 and older · All sexes · Updated Sep 16, 2026 · NCT01852448

Remote Sputum Collection in Cystic Fibrosis

RecruitingObservational study
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT06950892

Streamlined Treatment of Pulmonary Exacerbations in Pediatrics

Recruiting
  • Children's Hospital of Philadelphia & University of Pennsylvania, Philadelphia
Ages 3 to 18 · All sexes · Updated Aug 3, 2026 · NCT06654752

Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children

RecruitingObservational study
  • Children's Hospital of Philadelphia, Philadelphia
Up to age 10 · All sexes · Updated Jul 8, 2026 · NCT04509050

Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study

RecruitingPhase 4
  • University of Pennsylvania, Philadelphia
Ages 6 and older · All sexes · Updated Jul 8, 2026 · NCT05548283

4D-710 in Adult Patients With Cystic Fibrosis

RecruitingPhase 2
  • The Hospital of the University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT05248230

Study to Enable New Diagnostics for Pulmonary Microbes in People With CF

RecruitingObservational study
  • University of Pennsylvania, Philadelphia
Ages 16 and older · All sexes · Updated Jul 2, 2026 · NCT07312734

GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance

RecruitingPhase 2
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT04731272

ACT With CF Self-Help Toolkit

Recruiting
  • Thomas Jefferson University Hospital, Philadelphia
Ages 18 and older · All sexes · Updated Mar 3, 2026 · NCT07436351

Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

RecruitingObservational study
  • The Children's Hospital of Philadelphia, Philadelphia
Ages 12 and older · All sexes · Updated Feb 10, 2026 · NCT06837181

Beta-cell Response to Incretin Hormones in Cystic Fibrosis

RecruitingHealthy volunteers welcome
  • Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Jan 14, 2026 · NCT01851694

Health Outcomes of Parents With Cystic Fibrosis-Aim 2

RecruitingObservational study
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Nov 10, 2025 · NCT06296394

Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)

RecruitingObservational study
  • Nemours Children's, Wilmington · 25 mi away
Ages 6 and older · All sexes · Updated Nov 3, 2025 · NCT06683092

A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

RecruitingObservational study
  • Children's Hospital of Philadelphia, Philadelphia
  • University of Pennsylvania, Philadelphia
Ages 12 and older · All sexes · Updated Oct 1, 2025 · NCT06504589

A Phase 1/2 Trial of SP-101 for the Treatment of Cystic Fibrosis (CF)

RecruitingPhase 1/2
  • Hospital at University of Pennsylvania, Philadelphia
Ages 18 to 65 · All sexes · Updated Nov 25, 2024 · NCT06526923

About Cystic Fibrosis

Cystic fibrosis (CF) is an inherited disease of the mucus and sweat glands. The symptoms and severity of CF can vary. Get the facts.

More about Cystic Fibrosis on MedlinePlus

Cystic Fibrosis trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.