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Major Depressive Disorder clinical trials in Charlotte, NC

4 studies for Major Depressive Disorder are looking for participants at sites in and around Charlotte (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder

RecruitingPhase 3
  • Vanda Investigational Site, Charlotte
Ages 18 to 65 · All sexes · Updated Sep 24, 2026 · NCT06830044

NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 3
  • Neurocrine Clinical Site, Charlotte
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT06963021

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

RecruitingPhase 3
  • New Hope Clinical Research, Charlotte
Ages 18 to 74 · All sexes · Updated Aug 3, 2026 · NCT06775379

A Study to Evaluate the Maintenance Effect of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 3
  • Neurocrine Clinical Site, Charlotte
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT07196501

Major Depressive Disorder trials in other cities

Other studies in Charlotte

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.