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Metastatic Cancer clinical trials in Springfield, IL

4 studies for Metastatic Cancer are looking for participants at sites in and around Springfield (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

RecruitingPhase 2
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Clinic, Springfield
  • Springfield Memorial Hospital, Springfield
All ages · All sexes · Updated Oct 2, 2026 · NCT05564377

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

RecruitingPhase 3
  • Simmons Cancer Institute at SIU, Springfield
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • Springfield Clinic Main Campus, Springfield
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

RecruitingPhase 3
  • Southern Illinois University-Simmons, Springfield
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06072612

Metastatic Cancer trials in other cities

Other studies in Springfield

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.