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Healthy volunteer studies in San Antonio, TX

78 studies at sites in and around San Antonio accept healthy volunteers — people without the condition being studied. Many studies pay participants for their time and travel; the amount is set by each study, so ask the study team.

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Audie L Murphy VA Hospital, San Antonio
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

RecruitingHealthy volunteers welcome
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07091617

A Study to Evaluate the Impact of Renal Impairment on the Pharmacokinetics (PK) of Ribupatide

RecruitingPhase 1Healthy volunteers welcome
  • Kailera Clinical Site, San Antonio
Ages 18 to 85 · All sexes · Updated Oct 1, 2026 · NCT07793929

Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis

RecruitingPhase 1/2Healthy volunteers welcome
  • Xencor Investigative Site, San Antonio
Ages 18 to 75 · All sexes · Updated Sep 29, 2026 · NCT06619990

Ph 1a/1b Single Ascending Dose and Multiple Ascending Dose Study of ARQ-234

RecruitingPhase 1Healthy volunteers welcome
  • Clinical Site 104, San Antonio
Ages 18 to 65 · All sexes · Updated Sep 29, 2026 · NCT07453602

Fertilo In Vitro Research Study and Trial

RecruitingPhase 3Healthy volunteers welcome
  • Aspire Fertility San Antonio, San Antonio
Ages 18 to 35 · Women · Updated Sep 29, 2026 · NCT06858111

First-in-Human Trial to Assess REGN20423 in Healthy Adult Participants and Adult Participants With Atopic Dermatitis

RecruitingPhase 1Healthy volunteers welcome
  • Texas Dermatology and Laser Specialists, San Antonio
Ages 18 to 65 · All sexes · Updated Sep 25, 2026 · NCT07527923

Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older

RecruitingPhase 1/2Healthy volunteers welcome
  • DM Clinical Research - San Antonio - North San Saba- Site Number : 8400056, San Antonio
  • DM Clinical Research - San Antonio - North San Saba- Site Number : 8400057, San Antonio
Ages 60 and older · All sexes · Updated Sep 24, 2026 · NCT07734649

Behavioral Economic Intervention to Improve HIV Behaviors in Sexual Minority Individuals

RecruitingHealthy volunteers welcome
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 to 34 · All sexes · Updated Sep 23, 2026 · NCT06745947

Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)

RecruitingHealthy volunteers welcome
  • The University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 to 65 · All sexes · Updated Sep 22, 2026 · NCT02969798

Pioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants

RecruitingPhase 4Healthy volunteers welcome
  • Texas Diabetes Institute/UH, San Antonio
Ages 30 to 70 · All sexes · Updated Sep 22, 2026 · NCT05838287

Effect of Hepatic Impairment on the Pharmacokinetics of Mirdametinib

RecruitingPhase 1Healthy volunteers welcome
  • American Research Corporation (Texas Liver Institute), San Antonio
Ages 18 to 80 · All sexes · Updated Sep 21, 2026 · NCT06997276

A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age

RecruitingPhase 3Healthy volunteers welcome
  • GSK Investigational Site, San Antonio
Ages 65 and older · All sexes · Updated Sep 18, 2026 · NCT07805707

A Study to Evaluate the Effect of Moderate or Severe Hepatic Impairment on the Pharmacokinetics (PK) of Inavolisib

RecruitingPhase 1Healthy volunteers welcome
  • The Texas Liver Institute, Inc., San Antonio
  • Pinnacle Clinical Research - San Antonio, San Antonio
Ages 18 to 80 · All sexes · Updated Sep 18, 2026 · NCT07144111

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

RecruitingPhase 3Healthy volunteers welcome
  • ACCOMPLISH-2 Research Site, San Antonio
  • ACCOMPLISH-2 Research Site, San Antonio
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

A First-in-Human Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of HMB-003 in Healthy Volunteers

RecruitingPhase 1Healthy volunteers welcome
  • Worldwide Clinical Trials, San Antonio
Ages 18 to 50 · All sexes · Updated Sep 10, 2026 · NCT07798505

A Phase I Study to Investigate the Pharmacokinetics and Safety of Capivasertib in Participants With Moderate Hepatic Impairment

RecruitingPhase 1Healthy volunteers welcome
  • Research Site, San Antonio
Ages 18 to 80 · All sexes · Updated Sep 9, 2026 · NCT07343960

A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.

RecruitingPhase 3Healthy volunteers welcome
  • Sun Research Institute, San Antonio
42 Days – 211 Days · All sexes · Updated Sep 8, 2026 · NCT07629440

A First-in-human Research Study on How NNC0721-8060 Works in People Living With Overweight or Obesity

RecruitingPhase 1Healthy volunteers welcome
  • ICON, San Antonio
Ages 18 to 55 · All sexes · Updated Sep 4, 2026 · NCT07767175

A Study to Test How BI 1291583 is Taken up in the Blood of People With and Without Liver Problems

RecruitingPhase 1Healthy volunteers welcome
  • American Research Corporation at the Texas Liver Institute, San Antonio
Ages 18 to 80 · All sexes · Updated Sep 4, 2026 · NCT07023354

Comparative PK Assessment Study of Casdatifan in Moderate Hepatically Impaired Participants Versus Matched Participants With Normal Hepatic Function

RecruitingPhase 1Healthy volunteers welcome
  • Research Site, San Antonio
Ages 18 to 84 · All sexes · Updated Sep 4, 2026 · NCT07751250

A Study of LY4174794 in Participants With Obesity or Overweight Who Are Otherwise Healthy

RecruitingPhase 1Healthy volunteers welcome
  • ICON Early Phase Services, LLC, San Antonio
Ages 18 to 65 · All sexes · Updated Sep 1, 2026 · NCT07654972

A Phase I Study to Investigate the Effect of Hepatic Impairment of AZD9550 and AZD6234

RecruitingPhase 1Healthy volunteers welcome
  • Research Site, San Antonio
Ages 18 to 85 · All sexes · Updated Sep 1, 2026 · NCT07546760

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • San Antonio VA Medical Center, San Antonio
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents

RecruitingPhase 3Healthy volunteers welcome
  • Sun Research Institute, San Antonio
15 Months – 17 Years · All sexes · Updated Aug 31, 2026 · NCT07660198

A Study to Assess Zilucoplan Concentration in Breast Milk of Healthy Lactating Women

RecruitingPhase 1Healthy volunteers welcome
  • UP0137 2, San Antonio
Ages 18 and older · Women · Updated Aug 27, 2026 · NCT06961747

Advancing Skills Through Consultation, Education, and Novel Technologies

RecruitingHealthy volunteers welcome
  • University of Texas Health Science Center at San Antonio, San Antonio
All ages · All sexes · Updated Aug 24, 2026 · NCT07707102

Genetic of Skeletal Muscle Insulin Resistance

RecruitingHealthy volunteers welcome
  • Texas Diabetes Institute - University Health System, San Antonio, Texas 78207, San Antonio
Ages 18 to 75 · All sexes · Updated Aug 24, 2026 · NCT07780513

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight

RecruitingPhase 1Healthy volunteers welcome
  • ICON Early Phase Services, San Antonio
Ages 18 to 65 · All sexes · Updated Aug 20, 2026 · NCT07738614

First Time in Human Study of Long Acting VH4524184 Formulations

RecruitingPhase 1Healthy volunteers welcome
  • GSK Investigational Site, San Antonio
Ages 18 to 55 · All sexes · Updated Aug 10, 2026 · NCT06310551

A Study of LY4088044 in Healthy Participants

RecruitingPhase 1Healthy volunteers welcome
  • ICON Early Phase Services, San Antonio
Ages 18 to 65 · All sexes · Updated Aug 7, 2026 · NCT07090785

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

RecruitingObservational studyHealthy volunteers welcome
  • UT San Antonio Health Science Center, San Antonio
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04363684

Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth in/Near Infected Bone Cavities

RecruitingHealthy volunteers welcome
  • UT Health San Antonio, San Antonio
Ages 22 and older · All sexes · Updated Jul 14, 2026 · NCT05361941

Assessment of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of a New Formulation of Inclisiran Containing Polysorbate 80 Compared to the Currently Marketed Formulation

RecruitingPhase 1Healthy volunteers welcome
  • Cardiovasular Renal Metabolism, San Antonio
Ages 18 to 60 · All sexes · Updated Jul 10, 2026 · NCT07626281

Study of GS-4571 in Healthy Participants, Nondiabetic Obese Participants, and Nonobese Participants With Type 2 Diabetes Mellitus (T2DM)

RecruitingPhase 1Healthy volunteers welcome
  • ICON Early Phase Services, LLC, San Antonio
Ages 18 to 55 · All sexes · Updated Jun 22, 2026 · NCT06562907

Text-Based Messaging Strategies for Preventing Subsequent Problematic Alcohol Use

RecruitingHealthy volunteers welcome
  • JBSA Lackland, San Antonio
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT06318975

Pharmacokinetic Study of Vorasidenib in Severe Hepatically Impaired and Matched-Control Participants

RecruitingPhase 1Healthy volunteers welcome
  • American Research Corporation, San Antonio
Ages 18 to 75 · All sexes · Updated Jun 5, 2026 · NCT07250633

A Study of Eloralintide (LY3841136) in Participants With Different Levels of Liver Damage and in Participants With Healthy Livers.

RecruitingPhase 1Healthy volunteers welcome
  • American Research Corporation, San Antonio
Ages 18 to 85 · All sexes · Updated Jun 4, 2026 · NCT07401862

A Phase 1/2a Study of DB-2304 in Healthy Adults and SLE/CLE Participants

RecruitingPhase 1/2Healthy volunteers welcome
  • US02-0, San Antonio
Ages 18 to 70 · All sexes · Updated Jun 2, 2026 · NCT06625671

Modifying Adiposity Through Behavioral Strategies to Improve COVID-19 Rehabilitation

RecruitingHealthy volunteers welcome
  • South Texas Health Care System, San Antonio, TX, San Antonio
Up to age 80 · All sexes · Updated Jun 1, 2026 · NCT05880108

RESTOR: PK/PD mTORi Inhibition in Older Adults

RecruitingEarly phase 1Healthy volunteers welcome
  • The University of Texas Health Science Center at San Antonio, San Antonio
Ages 65 to 90 · All sexes · Updated Jun 1, 2026 · NCT06658093

Genomic Predictors of Recurrent Pregnancy Loss

RecruitingObservational studyHealthy volunteers welcome
  • University of Texas at San Antonio, San Antonio
Ages 18 to 50 · All sexes · Updated May 22, 2026 · NCT05444283

A Study of Mirikizumab Solution (LY3074828) in Healthy Participants

RecruitingPhase 1Healthy volunteers welcome
  • Worldwide Clinical Trials, Inc., San Antonio
Ages 18 to 65 · All sexes · Updated May 14, 2026 · NCT07446101

A Study to Test How BI 3000202 is Taken up in the Blood of People With and Without Liver Problems

RecruitingPhase 1Healthy volunteers welcome
  • American Research Corporation at the Texas Liver Institute, San Antonio
Ages 18 to 80 · All sexes · Updated May 14, 2026 · NCT07486102

The Role of Glucagon in Glucose Metabolism in Humans With and Without Bariatric Surgery

RecruitingPhase 1Healthy volunteers welcome
  • Texas Diabetes Institute - University Health System, San Antonio
  • University of Texas San Antonio, San Antonio
Ages 18 to 65 · All sexes · Updated May 11, 2026 · NCT07212868

Radiprodil in Participants With Hepatic Impairment

RecruitingPhase 1Healthy volunteers welcome
  • Texas Liver Institute, San Antonio
Ages 18 to 75 · All sexes · Updated May 8, 2026 · NCT07457229

Use of CA125 and Complementary Biomarkers for the Early Detection of Ovarian Cancer in Low Risk Women

RecruitingHealthy volunteers welcome
  • UT Health Science Center San Antonio, San Antonio
Ages 50 to 74 · Women · Updated May 6, 2026 · NCT00539162

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of EDP-978 in Healthy Adults

RecruitingPhase 1Healthy volunteers welcome
  • ICON Early Phase, San Antonio
Ages 18 to 65 · All sexes · Updated Apr 21, 2026 · NCT07540910

A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist Use

RecruitingPhase 3Healthy volunteers welcome
  • Vanda Investigational Site, San Antonio
Ages 18 to 65 · All sexes · Updated Apr 20, 2026 · NCT07446439

Quitxt Mobile Text Messaging Cessation Research Study

RecruitingHealthy volunteers welcome
  • The University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 to 29 · All sexes · Updated Mar 31, 2026 · NCT05958667

Neonatal Platelet Transfusion Threshold Trial

RecruitingHealthy volunteers welcome
  • Pediatrix Medical Group, San Antonio
1 Hour – 48 Hours · All sexes · Updated Mar 25, 2026 · NCT06676904

A Study to Evaluate the Effects of CYP2D6 Phenotypes on the Pharmacokinetics of Xanomeline Following KarXT Administration in Healthy Adult Participants

RecruitingPhase 1Healthy volunteers welcome
  • ICON Development Solutions, San Antonio
Ages 18 to 65 · All sexes · Updated Feb 19, 2026 · NCT07204418

Cognitive Screening Made Easy for PCPs - Administrative Supplement

RecruitingHealthy volunteers welcome
  • UT Health San Antonio's Geriatrics and Supportive Care Clinic, San Antonio
Ages 60 and older · All sexes · Updated Feb 5, 2026 · NCT06928298

Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study

RecruitingObservational studyHealthy volunteers welcome
  • University of Texas, San Antonio
Ages 18 and older · All sexes · Updated Jan 15, 2026 · NCT05677880

Wound Healing Following Tooth Extraction and Ridge Preservation Using OsteoGen®

RecruitingHealthy volunteers welcome
  • University of Texas Health Science Center at San Antonio School of Dentistry, San Antonio
Ages 18 to 89 · All sexes · Updated Jan 6, 2026 · NCT07154693

Chromosome 18 Clinical Research Center

RecruitingObservational studyHealthy volunteers welcome
  • University Health Systems Hospital, San Antonio
  • University of Texas Health Science Center at San Antonio, San Antonio
All ages · All sexes · Updated Jan 6, 2026 · NCT00227253

Passive Detection- SARS-CoV-2 (COVID-19) A&M Breathalyzer (PROTECT Kiosk) for Operational Medicine

RecruitingObservational studyHealthy volunteers welcome
  • Brooke Army Medical Center, Fort Sam Houston · 4 mi away
Ages 18 to 89 · All sexes · Updated Dec 10, 2025 · NCT06402318

A Study to Evaluate the SENSE Device's Ability to Detect TBI

RecruitingObservational studyHealthy volunteers welcome
  • UTSA, San Antonio
Ages 22 and older · All sexes · Updated Nov 25, 2025 · NCT06828107

Ultrasound for Healthy Aging

RecruitingHealthy volunteers welcome
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 70 and older · All sexes · Updated Nov 17, 2025 · NCT07168525

Microsurgery and Periodontal Healing

RecruitingHealthy volunteers welcome
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 to 18 · All sexes · Updated Nov 12, 2025 · NCT07054008

The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness

RecruitingHealthy volunteers welcome
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 to 18 · All sexes · Updated Nov 12, 2025 · NCT07053969

Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions

RecruitingObservational studyHealthy volunteers welcome
  • University of Texas Health Science Center, San Antonio
All ages · All sexes · Updated Oct 15, 2025 · NCT03160274

An Advanced Decision Support Tool for Personalized Medicine for IVF Using Modeling and Optimization for Provera

RecruitingPhase 1/2Healthy volunteers welcome
  • Positivf Fertility, San Antonio
Ages 20 to 50 · Women · Updated Sep 29, 2025 · NCT07148999

The Effects of Bariatric Surgeries on Glucose Metabolism

RecruitingEarly phase 1Healthy volunteers welcome
  • Texas Diabetes Institute - University Health System, San Antonio
  • South Texas Veterans Health Care System, San Antonio
Ages 18 to 65 · All sexes · Updated Sep 9, 2025 · NCT02823665

Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass

RecruitingEarly phase 1Healthy volunteers welcome
  • Texas Diabetes Institute - University Health System, San Antonio
  • South Texas Veterans Health Care System, San Antonio
Ages 18 to 65 · All sexes · Updated Sep 9, 2025 · NCT01803451

Role of Neural and Hormonal Regulation Factors on Insulin Secretion After Gastric Bypass Surgery

RecruitingEarly phase 1Healthy volunteers welcome
  • Texas Diabetes Institute - University Health System, San Antonio
  • South Texas Veterans Health Care System, San Antonio
Ages 18 to 65 · All sexes · Updated Sep 9, 2025 · NCT00992901

Combining Stellate Ganglion Block With Prolonged Exposure for PTSD

RecruitingPhase 2Healthy volunteers welcome
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 to 65 · All sexes · Updated Sep 4, 2025 · NCT05889741

Evaluation of a Device to Reduce Motion Sickness and Spatial Disorientation

RecruitingHealthy volunteers welcome
  • Randolph AFB Physiology lab, San Antonio
Ages 18 to 50 · All sexes · Updated Aug 15, 2025 · NCT06892340

CONTOURA vs WFO Ablation PRK & LASIK

RecruitingHealthy volunteers welcome
  • Joint Warfighter Refractive Surgery Center at WHASC, San Antonio
Ages 21 to 50 · All sexes · Updated Aug 14, 2025 · NCT05037370

Safety and Immunogenicity of a Self-Amplifying RNA Vaccine Against Crimean-Congo Hemorrhagic Fever

RecruitingPhase 1Healthy volunteers welcome
  • Flourish Research San Antonio (Clinical Trials of Texas), San Antonio
Ages 18 to 64 · All sexes · Updated Jul 28, 2025 · NCT06799013

Pharmacokinetics (PK) and Safety of Zanzalintinib in Participants With Moderate Hepatic Impairment (HI)

RecruitingPhase 1Healthy volunteers welcome
  • Exelixis Clinical Site #2, San Antonio
Ages 18 to 75 · All sexes · Updated Jun 22, 2025 · NCT06962332

InSpace Accelerated Rehabilitation Study

RecruitingHealthy volunteers welcome
  • TSAOG Orthopaedics & Spine, San Antonio
Ages 65 and older · All sexes · Updated May 29, 2025 · NCT05329584

Phosphatidylethanol and Other Ethanol Consumption Markers

RecruitingHealthy volunteers welcome
  • University of Texas Health Science Center San Antonio, San Antonio
Ages 21 and older · All sexes · Updated May 13, 2025 · NCT06747364

Collection of Sputum and Labeling for Lung Cancer

RecruitingObservational studyHealthy volunteers welcome
  • South Texas Veterans Health Care System (STVHCS)/Audie L. Murphy Memorial Veterans Hospital, San Antonio
Ages 21 and older · All sexes · Updated Apr 1, 2025 · NCT03457415

The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD

RecruitingPhase 4Healthy volunteers welcome
  • Brooke Army Medical Center, San Antonio
Ages 18 to 70 · All sexes · Updated Feb 25, 2025 · NCT06414356

Using SnapshotNIR With Provocative Leg Maneuver for PAD Assessment

RecruitingObservational studyHealthy volunteers welcome
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 35 to 99 · All sexes · Updated Oct 10, 2024 · NCT06237621

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.