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Prostate Cancer clinical trials in Ann Arbor, MI

27 studies for Prostate Cancer are looking for participants at sites in and around Ann Arbor (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

RecruitingPhase 3
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti · 7 mi away
  • Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea · 15 mi away
  • Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton · 18 mi away
Ages 18 and older · Men · Updated Oct 2, 2026 · NCT06931340

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

RecruitingPhase 3
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
Ages 18 and older · Men · Updated Oct 2, 2026 · NCT07200830

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
  • Huron Gastroenterology PC, Ypsilanti · 7 mi away
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti · 7 mi away
  • and 4 more
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

RecruitingPhase 2
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti · 7 mi away
  • Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea · 15 mi away
  • Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton · 18 mi away
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06632977

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

RecruitingPhase 2
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
  • Huron Gastroenterology PC, Ypsilanti · 7 mi away
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti · 7 mi away
  • and 4 more
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

Precision-Based Genomics in Prostate Cancer

RecruitingObservational study
  • University of Michigan, Ann Arbor
Ages 18 to 120 · Men · Updated Sep 28, 2026 · NCT04706663

Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer

RecruitingPhase 1/2
  • Research Site, Ann Arbor
Ages 18 to 130 · Men · Updated Sep 25, 2026 · NCT07181161

Carboplatin or Olaparib for BRcA Deficient Prostate Cancer

RecruitingPhase 2
  • VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT04038502

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

RecruitingPhase 3
  • University of Michigan ( Site 0005), Ann Arbor
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT06925737

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

RecruitingPhase 3
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
  • University of Michigan Rogel Cancer Center, Ann Arbor
  • Chelsea Hospital, Chelsea · 15 mi away
  • and 2 more
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213

Prostate Active Surveillance Study

RecruitingObservational study
  • University of Michigan, Ann Arbor
Ages 21 and older · Men · Updated Sep 2, 2026 · NCT00756665

COMPASS Study for Metastatic Castration-resistant Prostate Cancer

RecruitingObservational study
  • Rogel Cancer Center, Ann Arbor
Ages 18 and older · Men · Updated Aug 27, 2026 · NCT07050433

EDRN Prostate MRI Biomarker Study

RecruitingObservational study
  • University of Michigan, Ann Arbor
Ages 18 and older · Men · Updated Aug 17, 2026 · NCT03784924

Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer

RecruitingPhase 2
  • University of Michigan Health, Ann Arbor
Ages 18 and older · Men · Updated Aug 14, 2026 · NCT04812366

SPECT/CT Imaging for Dosimetry in 177Lu-PSMA-617 (Pluvicto) Therapy

RecruitingObservational study
  • University of Michigan Comprehensive Cancer Center, Ann Arbor
Ages 18 and older · Men · Updated Jul 27, 2026 · NCT07096999

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

RecruitingPhase 3
  • Veteran's Administration Medical Center - Ann Arbor, Ann Arbor
  • University of Michigan Rogel Cancer Center, Ann Arbor
  • University of Michigan - Brighton Center for Specialty Care, Brighton · 18 mi away
Ages 18 and older · Men · Updated Jul 14, 2026 · NCT06592924

Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.

RecruitingPhase 2
  • VA Ann Arbor Healthcare System, Ann Arbor
Ages 18 and older · Men · Updated Jun 15, 2026 · NCT05422911

Targeted Early Detection Program in Men at High Genetic Risk for Prostate Cancer

RecruitingObservational study
  • University of Michigan Rogel Cancer Center, Ann Arbor
Ages 35 to 70 · Men · Updated Jun 12, 2026 · NCT07645391

Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer

RecruitingPhase 1/2
  • University of Michigan Comprehensive Cancer Center, Ann Arbor
Ages 18 and older · Men · Updated May 5, 2026 · NCT06616155

Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

RecruitingPhase 2/3
  • VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor
Ages 18 and older · Men · Updated Apr 8, 2026 · NCT04787744

Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body

RecruitingPhase 3
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor
  • Huron Gastroenterology PC, Ypsilanti · 7 mi away
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti · 7 mi away
  • and 4 more
Ages 18 and older · Men · Updated Jan 22, 2026 · NCT06470243

A Self-Monitoring Platform for Tracking Medication Safety and Concerns in Cancer Patients

Recruiting
  • University of Michigan Comprehensive Cancer Center, Ann Arbor
Ages 18 and older · All sexes · Updated Jan 21, 2026 · NCT07291414

Post-prostatectomy Radiation Therapy--Moderate Versus Ultra-hypofractionated (Also Known as Stereotactic Body Radiation Therapy [SBRT])

RecruitingPhase 2
  • University of Michigan Rogel Cancer Center, Ann Arbor
Ages 18 and older · Men · Updated Jan 16, 2026 · NCT05038332

Randomized Phase II Trial of Targeted Radiation With no Castration for Mcrpc

RecruitingPhase 2Healthy volunteers welcome
  • VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor
Ages 18 and older · Men · Updated Dec 31, 2025 · NCT06084338

Interstitial Assessment of Architectural Heterogeneity in Prostate Cancer Using a Fine Needle Photoacoustic Probe

RecruitingObservational study
  • University of Michigan Rogel Cancer Center, Ann Arbor
Ages 40 to 80 · Men · Updated Nov 24, 2025 · NCT05965180

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Ann Arbor
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

RecruitingPhase 3
  • Saint Joseph Mercy Hospital, Ann Arbor
  • University of Michigan Comprehensive Cancer Center, Ann Arbor
  • Saint Joseph Mercy Chelsea, Chelsea · 15 mi away
  • and 1 more
Ages 18 and older · Men · Updated Sep 11, 2025 · NCT03678025

About Prostate Cancer

Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.

More about Prostate Cancer on MedlinePlus

Prostate Cancer trials in other cities

Other studies in Ann Arbor

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.