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Sickle Cell Disease clinical trials in New York City, NY

13 studies for Sickle Cell Disease are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)

RecruitingPhase 1
  • Mount Sinai Hospital, New York
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07187973

A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

RecruitingPhase 3
  • Columbia University Medical Center_New York_0, New York
  • Columbia University Medical Center_New York_0, New York
Ages 2 and older · All sexes · Updated Sep 18, 2026 · NCT06609226

A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD

RecruitingPhase 2/3
  • Icahn School of Medicine at Mount Sinai, New York
Ages 12 and older · All sexes · Updated Aug 18, 2026 · NCT05431088

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

RecruitingObservational study
  • Weill Cornell Medical College - New York Presbyterian Hospital, New York
All ages · All sexes · Updated Aug 17, 2026 · NCT04398628

Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis

RecruitingPhase 2
  • Mount Sinai Medical Center, New York
Ages 12 and older · All sexes · Updated Aug 14, 2026 · NCT06699849

Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease

RecruitingPhase 1/2
  • Columbia University Irving Medical Center, New York
  • Memorial Sloan Kettering, New York
Ages 12 to 50 · All sexes · Updated Jul 2, 2026 · NCT04819841

131I-apamistamab-based Conditioning for Hematopoietic Stem Cell Transplant (HSCT) in Advanced Sickle Cell Disease (SCD)

RecruitingPhase 1
  • Columbia University Irving Medical Center, New York
Ages 12 to 50 · All sexes · Updated Jun 10, 2026 · NCT07015684

Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

RecruitingObservational study
  • Columbia Presbytarian (NT-DMT), New York
Ages 3 to 20 · All sexes · Updated Jun 4, 2026 · NCT06941389

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

RecruitingPhase 3
  • New York Presbyterian Hospital - Morgan Stanley Children's Hospital, New York
Ages 12 to 35 · All sexes · Updated Mar 23, 2026 · NCT05477563

Minimizing Toxicity in HLA-identical Sibling Donor Transplantation for Children With Sickle Cell Disease

RecruitingPhase 2
  • Columbia University, New York
Ages 2 to 25 · All sexes · Updated Mar 10, 2026 · NCT03587272

A Long-term Follow-up Study in Patients Who Received BEAM-101

RecruitingObservational study
  • Columbia University Irving Medical Center, New York
Ages 14 to 37 · All sexes · Updated Jan 28, 2026 · NCT07373639

Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain

Recruiting
  • Weil Cornell Medical College, New York
Ages 16 to 30 · All sexes · Updated Jan 7, 2026 · NCT06374238

Cannabinoids for the Reduction of Inflammation and Sickle Cell Related Pain

RecruitingPhase 2
  • Mount Sinai Hospital, New York
Ages 18 and older · All sexes · Updated Oct 2, 2025 · NCT05519111

About Sickle Cell Disease

Sickle cell disease is a group of inherited disorders that affect your red blood cells. It can cause pain, anemia, and other problems. Learn about treatments.

More about Sickle Cell Disease on MedlinePlus

Sickle Cell Disease trials in other cities

Other studies in New York City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.