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Alzheimer's Disease clinical trials in Jacksonville, FL

8 studies for Alzheimer's Disease are looking for participants at sites in and around Jacksonville (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Dominantly Inherited Alzheimer Network (DIAN)

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic Jacksonville, Jacksonville
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT00869817

A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)

RecruitingPhase 2
  • Mayo Clinic in Florida, Jacksonville
Ages 55 to 85 · All sexes · Updated Sep 22, 2026 · NCT07589595

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

RecruitingPhase 3
  • Jacksonville Center for Clinical Research, Jacksonville
Ages 60 to 85 · All sexes · Updated Sep 17, 2026 · NCT06976203

Robotic-Enabled Microsurgical Intervention for Neurodegenerative Disease

Recruiting
  • Baptist Health Research Institute, Jacksonville
Ages 50 and older · All sexes · Updated Aug 24, 2026 · NCT07178210

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

RecruitingPhase 3
  • Mayo Clinic - Jacksonville, Jacksonville
Ages 18 to 75 · All sexes · Updated Aug 4, 2026 · NCT06563895

A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

RecruitingPhase 3
  • Jacksonville Center for Clinical Research, Jacksonville
Ages 55 and older · All sexes · Updated Jul 7, 2026 · NCT07602582

Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease

RecruitingPhase 4Healthy volunteers welcome
  • Mayo Clinic, Jacksonville
Ages 60 and older · Women · Updated Nov 24, 2025 · NCT03821857

Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers

RecruitingPhase 1/2Healthy volunteers welcome
  • Mayo Clinic Jacksonville, Jacksonville
Ages 18 to 80 · All sexes · Updated May 2, 2025 · NCT05395624

About Alzheimer's Disease

Alzheimer's disease is a brain disorder that slowly destroys memory and thinking skills. It's the most common cause of dementia among older adults.

More about Alzheimer's Disease on MedlinePlus

Alzheimer's Disease trials in other cities

Other studies in Jacksonville

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.