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Cardiovascular Disease clinical trials in Boston, MA

37 studies for Cardiovascular Disease are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

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ELEVATE-HFpEF Clinical Study

Recruiting
  • Tufts Medical Center, Boston
Ages 40 and older · All sexes · Updated Oct 2, 2026 · NCT06678841

Transition to Cardiac Rehabilitation (T2CR) to Address Barriers of Multimorbidity and Frailty

Recruiting
  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06244199

A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk

RecruitingPhase 3
  • Massachusetts General Hospital, Boston
Ages 45 to 80 · All sexes · Updated Sep 22, 2026 · NCT07613294

CV CARE: CardioVascular Care in PC Patients

Recruiting
  • Brigham and Women's Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · Men · Updated Sep 22, 2026 · NCT06202820

Product Surveillance Registry

RecruitingObservational study
  • Boston, Boston
All ages · All sexes · Updated Sep 18, 2026 · NCT01524276

Zenith® Fenestrated+ Clinical Study

Recruiting
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT04875429

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Recruiting
  • Massachusetts General Hospital, Boston
  • Brigham and Women's Hospital, Boston
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT03242642

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

Recruiting
  • Tufts Medical Center, Boston
  • Massachusetts General Hospital, Boston
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

Recruiting
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 to 85 · All sexes · Updated Sep 3, 2026 · NCT06703489

A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD

RecruitingPhase 2
  • Clinical Research Site, Boston
Ages 18 to 85 · All sexes · Updated Sep 2, 2026 · NCT07333183

Harmony-HHT: ATV-1601 in Participants With Hereditary Hemorrhagic Telangiectasia (HHT)

RecruitingPhase 1/2Healthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07601425

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • VA Boston Healthcare System, Boston
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

RecruitingPhase 3
  • Research Site, Boston
  • Research Site, Boston
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT07000357

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

RecruitingPhase 3
  • Brigham and Womens Hospital, Boston
Ages 50 to 105 · All sexes · Updated Aug 21, 2026 · NCT07136012

Groceries for Residents of Southeastern USA to Stop Hypertension

RecruitingHealthy volunteers welcome
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT06891911

Global Paradise System US Post Approval Study

RecruitingObservational study
  • Massachusetts General Hospital, Boston
  • The Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT06297291

The Oxford Risk Factors And Non-Invasive Imaging Study

RecruitingObservational study
  • Brigham and Women's Hospital, Boston
Ages 18 to 99 · All sexes · Updated Jul 31, 2026 · NCT05169333

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
  • Tufts Medical Center, Boston
  • Boston Medical Center Corporation, Boston
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

SPYRAL GEMINI Pilot Study

Recruiting
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 to 80 · All sexes · Updated Jun 24, 2026 · NCT06907147

EVOC - EVs in Obesity and Cardiometabolic Disease

RecruitingObservational study
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT06408961

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Recruiting
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

Longitudinal Real-world Clinical Outcomes Study on Symplicity Renal Denervation

RecruitingObservational study
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT07174622

WEARABLE-BP: Wearable Everyday Automated Readings to Enable Assessment of Blood Pressure Control

Recruiting
  • Mass General Brigham Hospital, Boston
Ages 21 to 85 · All sexes · Updated Apr 13, 2026 · NCT07523269

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Recruiting
  • St Elizabeth's Medical Center, Boston
  • Massachusetts General Hospital, Boston
  • Beth Israel Deaconess, Boston
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

RecruitingPhase 3
  • Joslin Diabetes Center, Boston
Ages 18 to 75 · All sexes · Updated Mar 24, 2026 · NCT06217302

PKP2-ACM Natural History Study

RecruitingObservational study
  • Boston Children's Hospital, Boston
Ages 12 and older · All sexes · Updated Feb 27, 2026 · NCT06644742

CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes

RecruitingPhase 3
  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
Ages 18 and older · All sexes · Updated Jan 9, 2026 · NCT05931276

Effects of Whole vs. Nonfat Milk Consumption on Body Composition in Children

RecruitingHealthy volunteers welcome
  • New Balance Foundation Obesity Prevention Center, Boston
Ages 9 to 12 · All sexes · Updated Jan 8, 2026 · NCT05464186

Determining the Benefits of Exercise on Cardiovascular Risk in PTSD

Recruiting
  • Massachusetts General Hospital, Boston
Ages 18 to 65 · All sexes · Updated Dec 2, 2025 · NCT07260032

Impact of Cognitive Behavioral Therapy on PTSD-CVD Link

Recruiting
  • Massachusetts General Hospital, Boston
Ages 18 to 65 · All sexes · Updated Sep 25, 2025 · NCT06429293

Mindfulness and Behavior Change to Improve Cardiovascular Health of Older People With HIV

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 50 and older · All sexes · Updated Sep 22, 2025 · NCT06001814

MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

Recruiting
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 to 110 · All sexes · Updated Feb 25, 2025 · NCT05908331

Treatment of Brain AVMs (TOBAS) Study

Recruiting
  • Boston Medical Center, Boston
Ages 5 and older · All sexes · Updated Aug 15, 2024 · NCT02098252

PARTNER 3 Trial - Aortic Valve-in-Valve

Recruiting
  • Brigham and Women's Hospital, Boston
All ages · All sexes · Updated May 10, 2024 · NCT03003299

Cardiovascular Disease trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.