🔎 Trials Near Me

Home › Colorectal Cancer › Indiana › Indianapolis

Colorectal Cancer clinical trials in Indianapolis, IN

18 studies for Colorectal Cancer are looking for participants at sites in and around Indianapolis (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer

RecruitingPhase 2
  • Indiana University, Simon Comprehensive Cancer Center, Indianapolis
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07659795

Colonoscopy vs Stool Testing for Older Adults With Colon Polyps

Recruiting
  • Richard L. Roudebush VA Medical Center, Indianapolis
Ages 65 to 82 · All sexes · Updated Oct 2, 2026 · NCT05612347

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #4, Indianapolis
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

RecruitingPhase 1
  • Indiana University Simon Comprehensive Cancer Center, Indianapolis
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Franciscan Health, Indianapolis
  • Franciscan Health Mooresville, Mooresville · 16 mi away
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers

RecruitingPhase 1
  • Community Health Network, Indianapolis
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06663319

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

RecruitingPhase 3
  • Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT05863195

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

RecruitingPhase 1
  • Indiana University (IU) School of Medicine, Indianapolis
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213791

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • Community Health Network, Indianapolis
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

RecruitingPhase 3
  • Community Health Network, Inc., Indianapolis
  • Hematology Oncology of Indiana, Indianapolis
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07284849

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Clinical Study Site, Indianapolis
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07228832

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • Riley Hospital for Children, Indianapolis
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • Community Health Network, Indianapolis
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06586515

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Community Health Network, Indianapolis
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04657068

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

RecruitingPhase 4
  • Indiana University, Indianapolis
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT06562543

The Food Environment, Microbial Cysteine Metabolism, and Cancer Disparities

Recruiting
  • University Hospital Clinical Research Center, Indianapolis
Ages 45 to 75 · All sexes · Updated May 14, 2026 · NCT07086833

About Colorectal Cancer

Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.

More about Colorectal Cancer on MedlinePlus

Colorectal Cancer trials in other cities

Other studies in Indianapolis

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.