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Colorectal Cancer clinical trials in Irvine, CA

10 studies for Colorectal Cancer are looking for participants at sites in and around Irvine (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

RecruitingPhase 2
  • UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05673148

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

RecruitingPhase 1
  • UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05803382

Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT Trial

RecruitingPhase 3
  • City of Hope at Irvine Lennar, Irvine
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07271355

A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • City of Hope at Irvine Lennar, Irvine
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06004245

Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer

RecruitingPhase 1
  • UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06102902

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Clinical Study Site, Irvine
  • Clinical Study Site, Irvine
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07228832

Testing the Effects of Exercise on Colorectal Cancer Development After Treatment With Pelvic Radiation Therapy for Prostate Cancer

Recruiting
  • City of Hope at Irvine Lennar, Irvine
Ages 40 to 80 · Men · Updated Aug 28, 2026 · NCT07790718

Minimal Residual Disease Testing for the Early Detection of Cancer Recurrence in Resectable Stage II-IV Colorectal Cancer Patients

Recruiting
  • City of Hope at Irvine Lennar, Irvine
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT07125729

Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer

RecruitingPhase 1
  • UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT06654037

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

RecruitingPhase 1/2
  • UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT05691491

About Colorectal Cancer

Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.

More about Colorectal Cancer on MedlinePlus

Colorectal Cancer trials in other cities

Other studies in Irvine

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.