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Brain Tumors clinical trials in Columbus, OH

11 studies for Brain Tumors are looking for participants at sites in and around Columbus (within about 30 miles). Open a study to see who can join and how to contact the study team.

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

RecruitingPhase 2
  • Ohio State University, Columbus
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07326566

SRS & Abemaciclib w/wo Imlunestrant in the Management of HR+/HER2- Breast CA Brain Metastases

RecruitingPhase 1/2
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT04923542

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

RecruitingPhase 2
  • Ohio State University Comprehensive Cancer Center, Columbus
  • Mount Carmel East Hospital, Columbus
  • Columbus Oncology and Hematology Associates Inc, Columbus
  • and 15 more
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04511013

Targeted Pediatric High-Grade Glioma Therapy

RecruitingObservational study
  • Nationwide Children's Hospital, Columbus
12 Months – 39 Years · All sexes · Updated Sep 8, 2026 · NCT05839379

A Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma

RecruitingPhase 2
  • The Ohio State University College of Medicine (OSUCOM), Columbus
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07428616

Study of Olutasidenib and Temozolomide in HGG

RecruitingPhase 2
  • Nationwide Children's Hospital, Columbus
Ages 12 to 39 · All sexes · Updated Sep 1, 2026 · NCT06161974

Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).

RecruitingPhase 2
  • Nationwide Children's Hospital, Columbus
Ages 1 to 26 · All sexes · Updated Aug 4, 2026 · NCT07680439

Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the Brain

RecruitingPhase 1/2
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT05588453

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

RecruitingPhase 2
  • Nationwide Children's Hospital, Columbus
12 Months – 39 Years · All sexes · Updated May 29, 2026 · NCT05843253

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

RecruitingPhase 1/2
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06810544

Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements

RecruitingPhase 1/2
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Apr 8, 2026 · NCT05987644

About Brain Tumors

A brain tumor is a growth of abnormal cells in the brain tissue. Learn the types of tumors, symptoms, how they are diagnosed and treatment options.

More about Brain Tumors on MedlinePlus

Brain Tumors trials in other cities

Other studies in Columbus

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.