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Overweight clinical trials in Orlando, FL

25 studies for Overweight are looking for participants at sites in and around Orlando (within about 30 miles). Open a study to see who can join and how to contact the study team.

Study of Olatorepatide in Adult Participants Living With Overweight or Obesity Without Diabetes

RecruitingPhase 2
  • Clinical Site Partners, LLC DBA Flourish Research, Winter Park · 5 mi away
  • K2 Medical Research Maitland LLC, Main Office, Maitland · 6 mi away
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07685808

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

RecruitingPhase 2
  • Charter Research - Winter Park /ID# 281968, Orlando
  • Florida Institute For Clinical Research /ID# 282739, Orlando
Ages 18 to 75 · All sexes · Updated Sep 29, 2026 · NCT07752979

Study to Assess the Effect and Safety of ALV-100 on Maintenance of Weight Loss

RecruitingPhase 2
  • Clinical Neuroscience Solutions, Orlando
Ages 18 to 75 · All sexes · Updated Sep 28, 2026 · NCT07837973

A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity

RecruitingPhase 3
  • Headlands Research Orlando, Orlando
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07794579

AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight

RecruitingPhase 3
  • Clinical Neuroscience Solution, Orlando
  • Florida Institute for Clinical Research, LLC, Orlando
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07720271

A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

RecruitingPhase 3
  • Florida Inst For Clin Res LLC, Orlando
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07668414

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

RecruitingPhase 3
  • Florida Hospital- Center for Pediatric Research, Orlando
  • Nemours Children's Health, Orlando
Ages 6 to 17 · All sexes · Updated Sep 24, 2026 · NCT06672549

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

RecruitingPhase 3
  • Orlando Health, Orlando
  • Digestive and Liver Center of Florida, Orlando
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937099

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

RecruitingPhase 3
  • Orlando Health, Orlando
  • Digestive and Liver Center of Florida, Orlando
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937086

A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight

RecruitingPhase 2
  • Charter Research - Winter Park, Orlando
Ages 18 to 75 · All sexes · Updated Sep 22, 2026 · NCT07589608

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

RecruitingPhase 3
  • Research Site, Ocoee · 10 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07784270

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

RecruitingPhase 3
  • Conquest Research, Winter Park · 5 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07353931

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

RecruitingPhase 3
  • West Orange Endocrinology, Ocoee · 10 mi away
Ages 45 to 99 · All sexes · Updated Sep 22, 2026 · NCT07037433

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

RecruitingPhase 3
  • Clinical Site Partners, LLC dba Flourish Research, Winter Park · 5 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07282600

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

RecruitingPhase 3
  • AURORA-1 Clinical Site, Winter Park · 5 mi away
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743463

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

RecruitingPhase 3
  • AURORA-2 Clinical Site, Winter Park · 5 mi away
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743450

Feasibility and Acceptability of a Pediatric Referral to Summer Day Camps to Treat Obesity in Children From Low-Income Households

Recruiting
  • University of Central Florida, Orlando
Ages 5 to 11 · All sexes · Updated Sep 14, 2026 · NCT07464015

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

RecruitingPhase 3Healthy volunteers welcome
  • ACCOMPLISH-2 Research Site, Ocoee · 10 mi away
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

RecruitingPhase 2
  • Charter Research - Winter Park, Orlando
Ages 18 to 75 · All sexes · Updated Sep 8, 2026 · NCT06143956

AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

RecruitingPhase 3
  • Florida Institute for Clinical Research, LLC, Orlando
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07533175

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)

RecruitingPhase 3
  • Florida Institute for Clinical Research, Orlando
  • Conquest Research - Winter Park, Winter Park · 5 mi away
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07684144

Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes

RecruitingPhase 3
  • Kailera Clinical Site, Orlando
  • Kailera Clinical Site, Orlando
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07284901

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

RecruitingPhase 3
  • Clinical Neuroscience Solutions - Orlando, Orlando
  • Combined Research Orlando Phase I IV, Orlando
  • Florida Institute for Clinical Research, Orlando
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07684235

Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)

RecruitingPhase 3
  • Clinical Neuroscience Solutions, Orlando
  • Florida Institute for Clinical Research, Orlando
Ages 18 to 99 · All sexes · Updated Aug 27, 2026 · NCT07575399

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

RecruitingPhase 3
  • ACCOMPLISH-1 Research Site, Ocoee · 10 mi away
Ages 18 to 79 · All sexes · Updated Aug 10, 2026 · NCT07654361

Overweight trials in other cities

Other studies in Orlando

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.