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Obesity clinical trials in Cleveland, OH

11 studies for Obesity are looking for participants at sites in and around Cleveland (within about 30 miles). Open a study to see who can join and how to contact the study team.

Comparing Reduction With ESD- Versus APC-TORe

RecruitingHealthy volunteers welcome
  • Cleveland Clinic Foundation, Cleveland
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06131281

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

RecruitingPhase 3
  • Cleveland Clinic, Cleveland
Ages 6 to 17 · All sexes · Updated Sep 24, 2026 · NCT06672549

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

RecruitingPhase 3
  • Velocity Clinical Research - Cleveland, Beachwood · 10 mi away
Ages 45 to 99 · All sexes · Updated Sep 22, 2026 · NCT07037433

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

RecruitingPhase 3
  • AURORA-2 Clinical Site, Cleveland
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743450

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

RecruitingPhase 3
  • AURORA-1 Clinical Site, Cleveland
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743463

Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes

RecruitingPhase 3
  • Kailera Clinical Site, Cleveland
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07284901

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

RecruitingPhase 3
  • Louis Stokes Clvlnd VA Med Ctr, Cleveland
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001

Fibrosis Lessens After Metabolic Surgery

RecruitingPhase 4Healthy volunteers welcome
  • Cleveland Clinic, Cleveland
Ages 18 to 75 · All sexes · Updated Jul 31, 2026 · NCT06374875

TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation

RecruitingPhase 2
  • Cleveland Clinic, Cleveland
Ages 18 to 80 · All sexes · Updated Jan 13, 2026 · NCT06802081

Effects of Assisted Robotic vs Laparoscopic Sleeve Gastrectomy

RecruitingHealthy volunteers welcome
  • Cleveland Clinic, Cleveland
Ages 18 to 70 · All sexes · Updated Dec 10, 2025 · NCT06425016

RESET System Pivotal Trial (Rev F)

Recruiting
  • Cleveland Clinic, Cleveland
Ages 22 to 65 · All sexes · Updated Jul 18, 2024 · NCT04101669

About Obesity

Read about the causes of obesity and find out what you can do to decrease your risk of its associated health issues.

More about Obesity on MedlinePlus

Obesity trials in other cities

Other studies in Cleveland

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.