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Obesity clinical trials in Philadelphia, PA

23 studies for Obesity are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

RecruitingPhase 2
  • Suburban Research Associates, West Chester · 24 mi away
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07783802

AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight

RecruitingPhase 3
  • UPA Ctr Weight and Eating Dis, Philadelphia
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07339423

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

RecruitingPhase 3
  • Thomas Jefferson University - Medicine/GI and Hepatology, Philadelphia
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937086

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

RecruitingPhase 3
  • Thomas Jefferson University - Medicine/GI and Hepatology, Philadelphia
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937099

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

RecruitingPhase 3
  • Abington Medical Specialists, Horsham · 16 mi away
  • Family Practice Associates, Wilmington · 25 mi away
Ages 45 to 99 · All sexes · Updated Sep 22, 2026 · NCT07037433

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

RecruitingPhase 3
  • Keystone Clinical Studies, Plymouth Meeting · 12 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07353931

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

RecruitingPhase 3
  • Abington Medical Specialists, Horsham · 16 mi away
Ages 18 to 99 · All sexes · Updated Sep 16, 2026 · NCT07037459

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

RecruitingPhase 3
  • AURORA-2 Clinical Site, Philadelphia
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743450

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

RecruitingPhase 3
  • AURORA-1 Clinical Site, Philadelphia
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743463

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

RecruitingPhase 3
  • Suburban Research Associates - West Chester Office, West Chester · 24 mi away
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07351045

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

RecruitingPhase 3Healthy volunteers welcome
  • ACCOMPLISH-2 Research Site, Philadelphia
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight

RecruitingPhase 3
  • UPA Ctr Weight and Eating Dis, Philadelphia
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07770841

A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

RecruitingPhase 4
  • Dermatology Associates of Plymouth Meeting, Plymouth Meeting · 12 mi away
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06857942

A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus

RecruitingPhase 3
  • Research Site, Philadelphia
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07784725

Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL

RecruitingPhase 2
  • Children's Hospital of Philadelphia, Philadelphia
Ages 7 to 25 · All sexes · Updated Aug 19, 2026 · NCT05082519

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

RecruitingPhase 3
  • Thomas Jefferson University, Philadelphia
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

RecruitingPhase 3
  • ACCOMPLISH-1 Research Site, Philadelphia
Ages 18 to 79 · All sexes · Updated Aug 10, 2026 · NCT07654361

An Acceptance-Based Healthy Lifestyle Intervention for Diverse Adolescents

RecruitingHealthy volunteers welcome
  • Drexel University, Philadelphia
Ages 14 to 19 · Women · Updated Jul 20, 2026 · NCT06147973

Weight Bias Reducation Intervention With Nursing Students Using Simulation: The BRAVE Study

Recruiting
  • Villanova University, Villanova · 11 mi away
Ages 18 to 35 · All sexes · Updated Jul 17, 2026 · NCT07334470

A Study to Investigate Why Overweight People Regain Weight After Losing Weight in a Behavioral Weight Loss Program

Recruiting
  • Drexel University, Philadelphia
  • University of Pennsylvania, Philadelphia
Ages 25 to 59 · All sexes · Updated Jun 12, 2026 · NCT05748158

Optimizing a Mobile Health Platform for Sleep Promotion and Obesity Prevention in Children

RecruitingHealthy volunteers welcome
  • Children's Hospital of Philadelphia, Philadelphia
Ages 8 to 12 · All sexes · Updated May 27, 2026 · NCT05703347

Feasibility of Semaglutide in Advanced Lung Disease

RecruitingPhase 1/2
  • University of Pennsylvania Perelman School of Medicine, Philadelphia
Ages 18 to 80 · All sexes · Updated Apr 21, 2026 · NCT05746039

RemI for Post-Bariatric Surgery Weight Regain

RecruitingHealthy volunteers welcome
  • Temple University, Philadelphia
Ages 18 to 70 · All sexes · Updated Apr 3, 2026 · NCT06292936

About Obesity

Read about the causes of obesity and find out what you can do to decrease your risk of its associated health issues.

More about Obesity on MedlinePlus

Obesity trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.