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Overweight clinical trials in Houston, TX

33 studies for Overweight are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

RecruitingPhase 3
  • Houston Research Institute, Houston
  • The Endocrine Center, Houston
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07668414

A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

RecruitingPhase 3
  • PlanIt Research, LLC (Monitoring Room), Houston
  • PlanIt Research, LLC, Houston
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07595549

A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity

RecruitingPhase 3
  • Biopharma Informatic, LLC, Houston
  • Care Access - Houston - Clinical Trials Center by Walmart & Care Access, Houston
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07794579

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

RecruitingPhase 2
  • PlanIt Research /ID# 282204, Houston
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT07752979

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

RecruitingPhase 3
  • McGovern Medical School, Houston
  • Texas Childrens Hospital, Houston
  • Dynamed Clinical Research, LP d/b/a DM Clinical Research, Houston
  • and 1 more
Ages 6 to 17 · All sexes · Updated Sep 24, 2026 · NCT06672549

A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

RecruitingPhase 3
  • The University of Texas Health Science Center at Houston, Bellaire · 7 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07321886

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

RecruitingPhase 3
  • Biopharma Informatic, LLC, Houston
  • Cardiovascular Specialists of Willowbrook, Houston
  • PlanIt Research, PLLC, Houston
  • and 2 more
Ages 45 to 99 · All sexes · Updated Sep 22, 2026 · NCT07037433

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

RecruitingPhase 3
  • Research Site, Houston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07784270

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

RecruitingPhase 3
  • Juno Research, Houston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07282600

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

RecruitingPhase 3
  • Juno Research, Houston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07392190

A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight

RecruitingPhase 2
  • PlanIt Research, PLLC, Houston
Ages 18 to 75 · All sexes · Updated Sep 22, 2026 · NCT07589608

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

RecruitingPhase 3
  • Care Access - Houston, Houston
  • JCCT - Juno Bellaire Site, Bellaire · 7 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07353931

Semaglutide for Post-Smoking Cessation Weight Management

RecruitingPhase 2Healthy volunteers welcome
  • The University of Texas Health Science Center at Houston, Houston
Ages 18 to 75 · All sexes · Updated Sep 21, 2026 · NCT06173778

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

RecruitingPhase 3
  • AURORA-2 Clinical Site, Houston
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743450

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

RecruitingPhase 3
  • Elevate Clinical, Houston
  • Houston Research Institute, Houston
  • Bellaire Clinical Research, LLC, Bellaire · 7 mi away
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07351045

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

RecruitingPhase 2
  • Juno Research, Houston
Ages 18 to 75 · All sexes · Updated Sep 14, 2026 · NCT06897475

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

RecruitingPhase 3
  • HRI ? Medical Center, LLC, Houston
  • Juno Research, LLC, Houston
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07351058

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

RecruitingPhase 3Healthy volunteers welcome
  • ACCOMPLISH-2 Research Site, Houston
  • ACCOMPLISH-2 Research Site, Houston
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes

RecruitingPhase 2
  • Biopharma Informatic, LLC, Houston
  • PlanIt Research, PLLC, Houston
  • Research Physicians Network, LLC, Houston
Ages 18 to 75 · All sexes · Updated Sep 8, 2026 · NCT07215559

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

RecruitingPhase 2
  • PlanIt Research, PLLC, Houston
Ages 18 to 75 · All sexes · Updated Sep 8, 2026 · NCT06143956

A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

RecruitingPhase 4
  • Center for Clinical Studies, Houston
  • Bellaire Dermatology Associates, Bellaire · 7 mi away
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06857942

AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

RecruitingPhase 3
  • PlanIt Research, PLLC, Houston
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07533175

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

RecruitingPhase 3
  • JCCT- Juno Northwest Houston, Houston
  • Biopharma Informatic, LLC, Houston
  • Johnson County Clinical Trials Juno Bellaire, Bellaire · 7 mi away
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07684235

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)

RecruitingPhase 3
  • JCCT- Juno Northwest Houston, Houston
  • Johnson County Clinical Trials Juno Bellaire, Bellaire · 7 mi away
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07684144

Efficacy and Safety of Ribupatide in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes

RecruitingPhase 3
  • Kailera Clinical Site, Bellaire · 7 mi away
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07284875

A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight

RecruitingPhase 3
  • DM Clinical, Houston
Ages 8 to 18 · All sexes · Updated Aug 31, 2026 · NCT07253285

Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)

RecruitingPhase 3
  • Biopharma Informatic, LLC, Houston
  • Research Physicians Network, LLC, Houston
Ages 18 to 99 · All sexes · Updated Aug 27, 2026 · NCT07575399

A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus

RecruitingPhase 3
  • Research Site, Houston
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07784725

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

RecruitingPhase 3
  • ACCOMPLISH-1 Research Site, Houston
  • ACCOMPLISH-1 Research Site, Houston
Ages 18 to 79 · All sexes · Updated Aug 10, 2026 · NCT07654361

Metformin IN Asthma for Overweight and Obese Individuals (MINA)

RecruitingPhase 2
  • Baylor College of Medicine, Houston
Ages 18 and older · All sexes · Updated Jan 16, 2026 · NCT06273072

Overweight trials in other cities

Other studies in Houston

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.